Development of the multispectral UV polarization reflectance imaging system (MUPRIS) for in situ monitoring of the UV protection efficacy of sunscreen on human skin

Nishino, Ken; Haryu, Yasushi; Kinoshita, Ayui; Nakauchi, Shigeki

doi:10.1111/srt.12697

Cited by 6 publications

(5 citation statements)

References 34 publications

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“…14 Importantly, multispectral imaging enabled data to be acquired over a large wavelength span, with full coverage of the HEV band. The use of multispectral cameras has been recently been evaluated for a range of applications, including in proposed methods for the determination of a UV photoprotection index and for measuring UV protection efficacy from multispectral reflectance, 15 and for characterising erythema zones after photo-exposure for calculating SPFs for sunscreens (European patent: WO 2020/148454). 16 Another advantage of the multispectral imaging technique is that the reflectance images can be used to visualize how evenly sunscreens have been spread during application.…”

Section: Discussionmentioning

confidence: 99%

In vivo method for evaluating sunscreen protection against high‐energy visible light

Le Digabel,

Filiol,

Lauze

et al. 2023

Acad Dermatol Venereol

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BackgroundOverexposure to sunlight can have many harmful biological effects on the skin, leading to skin cancer and photoaging. As ultraviolet (UV) radiation has been identified as a cause of DNA damage and oxidative stress in the skin, the photoprotection provided by sunscreens is evaluated through their ability to filter UV light, using the sun protection factor (SPF). However, recent data have shown that high‐energy visible (HEV) light can also cause biological skin damage.ObjectivesTo develop a new in vivo method for evaluating the protection provided by sunscreens across a broad range of wavelengths, including the HEV band, based on multispectral image analysis.MethodsThis study evaluated the absorption properties of six commercially available sunscreens (five SPF 50+ products containing organic UV filters, and one product containing the wide spectrum filter, phenylene bis‐diphenyltriazine [TriAsorB™]) and of a control product containing no filter. Multispectral images were acquired from the skin on the forearms of healthy volunteers, before and after application of the test products. Images taken with LEDs emitting light at wavelengths ranging from UV to infrared were used to generate light reflectance maps for each product. The levels of absorbance of light in the UV and visible bands were then calculated.ResultsThe product containing the wide spectrum filter exhibited significantly higher absorbance over the HEV band (380–450 nm) than the control product and the other commercial sunscreens. All the sunscreens tested showed the same level of absorbance at 365 nm (UVA).ConclusionsMultispectral imaging provides a simple and reliable in vivo method for assessing the real‐world protection provided by sunscreens against all forms of photo‐induced skin damage, including that induced by HEV radiation.

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Section: Discussionmentioning

confidence: 99%

In vivo method for evaluating sunscreen protection against high‐energy visible light

Le Digabel,

Filiol,

Lauze

et al. 2023

Acad Dermatol Venereol

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“…However, recently some sunscreens are available which protect our skin immediately against UV radiation. Recent studies showed that sunscreen can remain on our skin at its desired SPF for as long as 8 hours and reapplication is suggested, if the sunscreen is removed by sweating, friction, water immersion (15). Spray sunscreens are less popular than the cream-based sunscreen because the wind can disperse the sunscreen, resulting in inadequate application and aerosolized sunscreens are flammable.…”

Section: Methods Of Application Of Sunscreenmentioning

confidence: 99%

Herbal microsponge incorporated sunscreen gel: A novel strategy

Das¹,

Chakraborty²,

Khatiwara³

et al. 2022

Biomedicine

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Different dermatological disorders have different effects on the lives of patients. Recently microsponge formulations have been used to treat several dermatological complications. Microsponges are basically tiny sponge like spherical particles with porous surface having valuable and attractive effect on topical delivery. The side effect of the used drug can be reduced, bioavailability can be increased, and the drug release can be modified. Microsponges can be used in different bases like gel, lotion, ointment and even in powder form. Microsponges used in sunscreen gel are now very popular. Excessive UV exposure leads to different pathological conditions like skin burns, erythema, skin carcinogenesis, etc., The microsponge sunscreen gel protects our skin from all these skin problems and most importantly, with a very less amount of side effects compared to others. Moreover, microsponges are very much cost effective, easy to handle, can deliver minimum dose of drug and enhance the stability.

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“…The technique has already been evaluated as a potential method for carrying out noninvasive analysis of the skin for applications such as erythema characterization 14 and SPF measurement. 15 The aim of the current study was to determine if multispectral imaging could be used as a reliable and rapid technique for assessing the real dose of an SPF 50+ sunscreen applied to the face of healthy volunteers, and evaluate the impact of providing application instructions or reapplying the sunscreen on the amount of sunscreen applied and the heterogeneity of the application across different areas of the face.…”

Section: Introductionmentioning

confidence: 99%

“…Multispectral imaging is a versatile technique that permits the acquisition of reflectance images of the skin at specific wavelengths. The technique has already been evaluated as a potential method for carrying out noninvasive analysis of the skin for applications such as erythema characterization 14 and SPF measurement 15 …”

Section: Introductionmentioning

confidence: 99%

In vivo evaluation of sunscreen application by multispectral imaging: A new tool for educating sunscreen users

Digabel

Questel

Lauze

et al. 2023

Skin Research and Technology

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BackgroundThe sun protection factor (SPF) of sunscreens is evaluated using standardized protocols based on the application of 2 mg/cm2 of product. However, the amount of product applied by sunscreen users in real life is likely to be much lower.ObjectivesTo evaluate a new multispectral imaging approach for determining the actual quantity of sunscreen applied by users and to assess the benefits of an application guide for the use of an SPF 50+ sunscreen.Materials and methodsAnalyses of the reflectance spectra obtained from multispectral images were used to determine the actual dose of sunscreen that 26 healthy volunteers applied to their face following three application modalities: a single application, reapplication after 30 min, and application according to an instruction guide.ResultsWithout the application guide, volunteers applied an average of 1.04 mg/cm2 of sunscreen during the single application and 1.23 mg/cm2 during the repeated application. With the application guide, the amount of sunscreen applied was 1.45 mg/cm2: around 40% higher than during the single application. Spreading of the sunscreen was also less uniform with the unguided single application than with the other application modalities.ConclusionsThis study showed that the multispectral imaging approach can be used to measure the amount of sunscreen applied in vivo. Our findings confirmed that the standard dose used for SPF measurements and other sunscreen tests is far higher than that applied by users in practice. Providing users with precise guidelines could increase the amount of sunscreen applied, resulting in more adequate photoprotection.

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Development of the multispectral UV polarization reflectance imaging system (MUPRIS) for in situ monitoring of the UV protection efficacy of sunscreen on human skin

Cited by 6 publications

References 34 publications

In vivo method for evaluating sunscreen protection against high‐energy visible light

In vivo method for evaluating sunscreen protection against high‐energy visible light

Herbal microsponge incorporated sunscreen gel: A novel strategy

In vivo evaluation of sunscreen application by multispectral imaging: A new tool for educating sunscreen users

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