Development of the system for abdominal aortic aneurysm mechanical properties research using “Bubble Inflated” method

Abstract

The main goal of this paper was to determine the biomechanical parameters of abdominal aortic aneurysm using the Bubble Inflated method. In other words, the main task of this paper was to develop a system which would be able to increase the pressure of physiological saline which affects blood vessel tissue and causes its deformation. This deformation is recorded using a camera and providing data at each moment about pressure values which affect tissue and were detected by using a pressure sensor. [Projekat Ministarstva nauke Republike Srbije, br. III41007 i br. OI-175008]

Software and hardware systems for abdominal aortic aneurysm mechanical properties investigation

“…The sensor is supplied with a voltage 12-36 VDC, and outputs a current of 4-20 mA, which reflects the change in pressure of the physiological saline. A heater is used to heat the distilled water in order to adjust the temperature of the physiological saline to 37°C, regardless of their physical mixing, since heating the physiological saline in the heater is not allowed in order to prevent chemical reactions that could alter the composition of the physiological saline [12].…”

Study of multi-axial failure properties of planar biological soft tissues

“…Additional synthetic materials were investigated using the inflation test because the materials tested were to be used under inflation in practice. Subsequent bubble inflation tests were implemented using biological tissues that included liver 32 , bovine tissue 29 , abdominal aortic aneurysm tissue 14 and thoracic aortic tissue 14,[32][33][34][35] Figure 10) 33,37 . However, simpler BIT systems have been implemented that only record peak stress and maximum deformation through optical measurements 14,29,34,35,38 .…”

“…Multiaxial failure properties have been studied by various groups with varying degrees of information that can be extracted from the bubble inflation test 14,[33][34][35][36][37] . Two different BIT apparatus' will be built, one that is manually pressurized with manual measurements of optical strain (Manual BIT) and the other that is automatically pressured with automated optical strain measurements (automated BIT).…”

“…Comparison between multiaxial and uniaxial failure properties is of great interest as uniaxial extension has been the primary mode of understanding material strength in biological soft tissues 14,33,35…”

“…Several materials were investigated including non-fibrous silicone, fibrous bacterial cellulose and bovine aorta. As mentioned previously, several groups have begun to look at multiaxial failure properties14,[33][34][35][36]75 and have found material heterogeneity during experimentation. The capabilities of the automatic BIT did not include localized stress calculations, therfore localized material heterogeneity cannot be addressed.…”