Tinospora cordifolia is a medicinal ayurvedic herb having vast benefit to human health. It is come under the climbing shrub, which belongs to family Menispermaceae and is inherent to India and some extent to China also, and some parts of Australia and Africa. Other names used for Tinospora cordifolia are Guduchi or Amrita or Giloy. Not a single part but whole plant has its own pharmacological effect for human well-being. Tinospora cordifolia has chemical constituents like terpenoids, alkaloids, steroids, lignans, flavonoids and glycosides. It has many pharmacological activities such as immunomodulation, anti-diabatic, antifungal, in hepatotoxicity (hepatic disorder), anti- cancer, anti-HIV potential, antitoxic effect, and in Parkinson disease. This review paper will discuss about the various properties/activities of the plant.