Developmental and behavioral toxicity assessment of glyphosate and its main metabolite aminomethylphosphonic acid (AMPA) in zebrafish embryos/larvae

The Herbicide Glyphosate and Its Formulations Impact Animal Behavior across Taxa

“…One study of larval zebrafish showed an increase in activity when exposed to GBH at the concentrations of 0.1 and 10 µM for a 7-day exposure period [118]. However, another study done on larval zebrafish showed an increase in activity levels when exposed to Roundup ® at 10 6 to 10 4 dilution but a decrease when exposed to GBH at 0.01 and 0.1 µM.…”

Monitoreo preliminar de glifosato y su principal metabolito en aguas superficiales de la cuenca del Río Santa Lucía y en agua potable

“…La transformación microbiológica aeróbica del GLY ha sido identificada como la principal vía de degradación, generando el metabolito ácido aminometilfosfónico (AMPA) (Guijarro et al, 2018). AMPA presenta tiempos de vida media en suelo y agua mayores al GLY, por lo que también interesa conocer su ecotoxicidad y sus niveles en el ambiente (Sun et al, 2019;Ivantsova et al, 2022;Bonansea et al, 2017).…”

Gold Nanoclusters and Silica-Coated Carbon Dots-Assisted Ratiometric Fluorescent Nanosensors for Ultrasensitive Detection of Glyphosate

“…Glyphosate ( N -[phosphonomethyl] glycine) with fascinating herbicidal activity has been extensively used worldwide as a broad-spectrum nonselective herbicide in modern agricultural, forest, and aquatic systems for weed and vegetation control. , Annual global production and its utilization is increasing since 1995 . However, glyphosate can transfer from target weed to nontarget plant, then to soil, water, and atmosphere, thus inhibiting the micronutrient availability and plant growth. , In addition, due to its toxicity and negative impacts on cell apoptosis and autophagy to cause potential risks, even death of humans, glyphosate has been classified probably as a group 2A carcinogen to humans . The large-scale use and abuse of glyphosate may cause the high-level residue to significantly affect the quality and safety of agricultural products, and its continuous long-term exposure may pose persistent damage to the environment and human health. − Thus, developing a convenient and universal method for glyphosate monitoring is important and urgent.…”

“…3 However, glyphosate can transfer from target weed to nontarget plant, then to soil, water, and atmosphere, thus inhibiting the micronutrient availability and plant growth. 3,4 In addition, due to its toxicity and negative impacts on cell apoptosis and autophagy to cause potential risks, even death of humans, glyphosate has been classified probably as a group 2A carcinogen to humans. 5 The large-scale use and abuse of glyphosate may cause the high-level residue to significantly affect the quality and safety of agricultural products, and its continuous long-term exposure may pose persistent damage to the environment and human health.…”