Developmental Pathology and Pedodontology

Shope, Bonnie; Mitchell, Paul Q.; Carle, Diane

doi:10.1002/9781118816219.ch4

Cited by 15 publications

(10 citation statements)

References 81 publications

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“…Three cats were of younger ages, with a history of juvenile gingivitis and periodontitis that progressed to FCGS. This association also has been previously reported [18,19].…”

Section: Discussionsupporting

confidence: 90%

Placebo-Controlled Trial of Daily Oral Cannabidiol as Adjunctive Treatment for Cats with Chronic Gingivostomatitis

Coelho,

Duarte,

Bento da Silva

et al. 2023

Animals

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A placebo-controlled study evaluated the clinical efficacy and safety of a commercially available cannabidiol (CBD) oral formulation as an adjunctive treatment for pain management for feline chronic gingivostomatitis (FCGS). CBD was included in a multimodal treatment routinely performed on client-owned cats with FCGS that were submitted to dental extractions. Twenty-two cats were consecutively included in the study. The first group was treated using a fixed dosage of 4 mg per cat every 12 h for 15 consecutive days, and the second received a placebo of similar features. Treatments began 2 h before dental extractions. Pain and disease severity were assessed at days 0 and 15 using the Composite Oral Pain Scale (COPS-C/F) and the Stomatitis Disease Activity Index score (SDAI). Weight, vital and biochemistry parameters, and analgesic reinforcement needs were also registered at the same time points. In the treated cats, blood was collected after 4, 8, and 12 h to determine CBD serum concentrations using ultra-high-performance liquid chromatography–mass spectrometry (UHPLC-MS/MS). After data analysis using mixed models, a significant improvement in the SDAI scores of cats medicated with CBD was found. The protocol is safe since severe adverse effects and biochemical changes were not observed during the treatment period. This study suggests that the cats benefited from this treatment.

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“…Three cats were of younger ages, with a history of juvenile gingivitis and periodontitis that progressed to FCGS. This association also has been previously reported [18,19].…”

Section: Discussionsupporting

confidence: 90%

Placebo-Controlled Trial of Daily Oral Cannabidiol as Adjunctive Treatment for Cats with Chronic Gingivostomatitis

Coelho,

Duarte,

Bento da Silva

et al. 2023

Animals

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“…Firstly, this dog was only 3months-old when the lesion was discovered by the owners and 4-months-old at the time of surgery, and secondly at that age the premolars and molars are not expect to be erupted. 15 However, in this case, the tip of the crowns of all the teeth that were expected in that area were recognizable, despite the young age (Figure 2). This case presented clinically with a large nonpainful bony swelling on the face.…”

Section: Discussionmentioning

confidence: 73%

Maxillary Aneurysmal Bone Cyst in a Young Dog—A Case Report

2023

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This case report describes an aneurysmal bone cyst in the maxilla of a young dog. It describes the clinical presentation, diagnostics, management, and successful outcome of this highly unusual case. Bone cysts are described as benign, cavitated lesions within bone that are lined by reactive tissues. There is no epithelial lining in the lesions. Bone cysts usually contain hemorrhage or serosanguinous fluid. They usually appear in the long bones, and present as a swelling with or without pain.

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“…Normal dental eruption times for cats have been previously published. 11,12 This cat was 5-months-old at the time of presentation at which age the crowns of all adult dentition should be erupted.…”

Section: Discussionmentioning

confidence: 99%

“…Therapy was started when the cat was less than six months of age and the adult dentition still had eruption potential. 11,12 Dose adjustments were made at 4-week intervals which mimics thyroid hormone spikes documented in developmentally normal kittens. 13 It is interesting to note that these spikes in thyroid hormones in clinically normal kittens at six weeks and 10 weeks of age align with the completion of eruption of deciduous dentition and the initiation of eruption of adult dentition in the healthy cat.…”

Section: Discussionmentioning

confidence: 99%

Medical Management of Dental Abnormalities Related to Congenital Hypothyroidism in a Cat

Bates¹

2023

J Vet Dent

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A 5-month-old intact male domestic shorthair cat presenting for routine vaccinations was diagnosed with congenital hypothyroidism. His primary presenting symptom was incomplete dentition with delayed dental eruption. Congenital hypothyroidism was confirmed by baseline thyroxine (T4), free T4, and thyroid-stimulating hormone testing. The cat was treated with oral thyroid hormone supplementation and 16 weeks after initiation of therapy the cat was clinically normal with age-appropriate dentition. No surgical intervention was necessary to achieve normal dental eruption.

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Developmental Pathology and Pedodontology

Cited by 15 publications

References 81 publications

Placebo-Controlled Trial of Daily Oral Cannabidiol as Adjunctive Treatment for Cats with Chronic Gingivostomatitis

Placebo-Controlled Trial of Daily Oral Cannabidiol as Adjunctive Treatment for Cats with Chronic Gingivostomatitis

Maxillary Aneurysmal Bone Cyst in a Young Dog—A Case Report

Medical Management of Dental Abnormalities Related to Congenital Hypothyroidism in a Cat

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