Developments in the laboratory diagnosis of SARS—coronavirus infections

Defects in the BRCA tumor suppressor genes contribute significantly to the development of breast cancer in South Africa. Additive genetic effects and lifestyle risk factors underlie variable expression patterns in affected families, while also increasing breast cancer risk in the general population. Modifiable environmental factors could determine whether individuals with genetic risk factors develop cancer or fail to respond to treatment. Consequently, there is an increasing demand for genetic testing not only in patients with familial breast cancer, but also in healthy women and patients with sporadic cancer. Today, genetic testing in breast health extends from single-gene diagnostic tests to multi-gene treatmentbased tests. For women in whom established breast cancer risk reduction approaches such as surgery and pharmaceuticals are not acceptable or inappropriate, treatment is based on molecular-genetic targets for individualised medical, nutrition and lifestyle intervention. Genetic testing as part of a holistic approach to breast health management translates into individual needs-based risk reduction interventions.

show abstract

The role of molecular genetic testing in modern breast heath management

Kotze¹,

Malan

Pienaar

et al. 2005

South African Family Practice

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Developments in the laboratory diagnosis of SARS—coronavirus infections

Cited by 1 publication

References 4 publications

The role of molecular genetic testing in modern breast heath management

The role of molecular genetic testing in modern breast heath management

Contact Info

Product

Resources

About