Devenir à moyen et long terme des enfants atteints d’atrésie de l’œsophage

Gottrand, Frédéric; Sfeir, Rony; Thumerelle, C.; Gottrand, L.; Fayoux, P.; Storme, Laurent; Lamblin, Marie‐Dominique; Séguy, D.; Michaud, Laurent

doi:10.1016/j.arcped.2012.06.012

Cited by 9 publications

(6 citation statements)

References 39 publications

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“…The mortality rate was 87.5%, a rate significantly higher than that found in the African series in which it varies between 60 and 75% [4,7,11]. This result contrasts with European series in which the mortality is almost zero [5,6,15]. It is however lower than that found by Leis and al. in Kabul, which is close to 100% [21].…”

Section: Discussioncontrasting

confidence: 57%

“…averagely 8.4 days with extremes of 0 and 21 days [7]. These figures are quite opposite to those in the Western series in which care is achieved within 24 to 48 hours of birth [5,13,15]. The delay in treatment in our context is explained on one hand by the delay in diagnosis, but on the other hand by the difficulties that patients' families have to face the often-expensive costs of surgery and preoperative resuscitation.…”

Section: Discussionmentioning

confidence: 66%

“…in 2016 in Dakar and Mbaye and al. in 2015, but contrasting with the results of Gottrand and al. who in a study done in France in 2012 on the antenatal diagnosis of oesophageal atresia, showed that in 66.6% of cases, the diagnosis of OA was suspected before birth [4,5,7]. Antenatal diagnosis allows referral of patients to a hospital capable of providing adequate care for the disease within twentyfour hours of birth.…”

Section: Discussionmentioning

confidence: 99%

“…It is an extreme neonatal surgical emergency which when present, heavily affects neonates in Cameroon and Sub-Saharan Africa generally, with mortality rates between 70% and 100% depending on the series [1][2][3][4]. These figures are inconsistent with those of the Western series, notably that of Gottrand and al. which reports less than 5% mortality in its series in France, and of Lilja et al in Sweden which notes 0% mortality in isolated forms [5,6]. With the aim of reversing this trend, we initially wished to describe here the epidemiological, diagnostic and therapeutic profile of deceased patients with oesophageal atresia in our context.…”

Section: Introductionmentioning

confidence: 96%

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Mortality of Oesophageal Atresia in a Low-Income Setting: About 21 Cases

Sadjo, et al...

2023

JAFRCHIR

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Introduction: Oesophageal atresia (OA) is an extreme neonatal neonatal surgical emergency which when present, heavily affects the neonate, in Cameroon and in Sub-Saharan Africa generally. The aim of our study was to describe the epidemiological, diagnostic and therapeutic characteristics of deceased patients with oesophageal atresia in our context. Methodology: We conducted an observational, descriptive, retrospective study over a period of 14 years, from the 1st January 2005 to the 28th February 2019. All paediatric patients who died from oesophageal atresia were included. Survivors were excluded (n = 3). Results: Mortality from oesophageal atresia was 87.5% in our series. The average age at the time of presentation was 5.2 days. The notion of attempted feeding at birth was found in 72.2% (n = 13). No antenatal diagnosis was noted. The lung condition was preoccupying in 61% of cases (n = 11). The average operating time was 7 days. Death before any surgical procedure concerned 22.2% of newborns (n = 4). Posterolateral thoracotomy with fistulectomy and oeso-oesophageal anastomosis represented 22.2% of our series (n = 4) while a feeding gastro jejunostomy was done in 66.6% of cases. Two deceased patients had undergone a feeding gastro-jejunostomy followed by a posterolateral thoracotomy. Conclusion: Knowledge of these epidemiological, diagnostic and therapeutic characteristics is a prerequisite for considering an inversion of the mortality curve for oesophageal atresia in our context.

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Section: Discussioncontrasting

confidence: 57%

Section: Discussionmentioning

confidence: 66%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 96%

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Mortality of Oesophageal Atresia in a Low-Income Setting: About 21 Cases

Sadjo, et al...

2023

JAFRCHIR

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“…The presence of dysphagia in children with severe tracheomalacia suggests a relationship between gastrointestinal and pulmonary symptoms. In fact GER, dysmotility, anastomotic strictures are risk factors for aspiration and worsening tracheomalacia [ 17 – 19 ].…”

Section: Introductionmentioning

confidence: 99%

Respiratory problems in children with esophageal atresia and tracheoesophageal fistula

et al. 2017

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Background: Children with congenital esophageal atresia (EA) and tracheoesophageal fistula (TEF) have chronic respiratory symptoms including recurrent pneumonia, wheezing and persistent cough. The aim of this study is to describe the clinical findings of a large group of children with EA and TEF surgically corrected and the instrumental investigation to which they have undergone in order to better understand the patient's needs and harmonize the care. Methods: A retrospective data collection was performed on 105 children with EA and TEF followed at Department of Pediatric Medicine of Bambino Gesù Children's Hospital (Rome, Italy) between 2010 and 2015. Results: 69/105 (66%) children reported lower respiratory symptoms with a mean age onset of 2.2 ± 2.5 years and only 63/69 (91%) performed specialist assessment at Respiratory Unit. Recurrent pneumonia (33%) and wheezing (31%) were the most reported symptoms. The first respiratory evaluation was performed after surgically correction of gastroesophageal reflux (GER) at mean age of 3.9 ± 4.2 years. Twenty nine patients have undergone to chest CT with contrast enhancement detecting localized atelectasis (41%), residual tracheal diverticulum (34%), bronchiectasis (31%), tracheal vascular compression (21%), tracheomalacia (17%) and esophageal diverticulum (14%). Fifty three patients have undergone to airways endoscopy detecting tracheomalacia (66%), residual tracheal diverticulum (26%), recurrent tracheoesophageal fistula (19%) and vocal cord paralysis (11%). Conclusions: Our study confirms that respiratory symptoms often complicate EA and TEF; their persistence despite medical and surgical treatment of GER means that other etiological hypothesis must be examined and that a complete respiratory diagnostic work up must be considered.

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