Dexamethasone prophylaxis before thyroidectomy to reduce postoperative nausea, pain, and vocal dysfunction: A randomized clinical controlled trial

Abstract

Dexamethasone (8 mg IV) is a safe and effective method to reduce PONV and pain after thyroid resection and should be used routinely.

Study Of Efficacy Of Dexamethasone As Preemptive Analgesic In Patients Undergoing Total Abdominal Hysterectomy Under Spinal Anaesthesia: A Randomised Controlled Trial

“…There appears to be no added advantage of preoperative administration of Dexamethasone over intraoperative administration with respect to PONV. Our results are in line with studies by Thangaswamy C et al (18) , Jun Koh et al (27) , Feroci et al (26) , Mathisen et al (29) , Hermans et al (30) . We monitored patients throughout study period with respect to pulse rate , mean arterial pressure and SpO 2.…”

“…Our result match with Aissaoui Y et al (25) ,Thangaswamy C at al (18) , Ahmadreza M et al (19) , Becky et al (21) , Feroci et al (26) . There are studies by José at al (20) , Jun Koh et al (27) where they evaluated the timing of first rescue analgesic and total analgesic requirement for longer duration postoperatively.…”

Clinical Practice Guideline: Improving Voice Outcomes after Thyroid Surgery

“…Corticosteroid medications are potent inhibitors of inflammatory responses and have been used in single-dose administration during the perioperative period in thyroid surgery to significantly reduce postoperative nausea and pain. 81,203 While the mechanism by which corticosteroids exert a beneficial effect on nausea and pain is likely to be different than how they might impact voice changes that occur after thyroid surgery, the possibility exists that corticosteroids may also improve voice outcomes by preventing the development of anatomical abnormalities that might result in abnormalities of voice.…”

“…One randomized, doubleblind, controlled study administered a single preoperative dose of dexamethasone (8 mg) intravenously to 1 of 2 cohorts (n = 51) and compared the rate of postoperative nausea and vomiting (primary outcome measure), pain, and subjective vocal function (voice visual analog scale 0-100) to a second cohort (n = 51) after total thyroidectomy or lobectomy for benign disease. 203 Potential adverse events associated with corticosteroid use including hyperglycemia, infection, delayed wound healing, and cardiovascular abnormalities were also collected, but not reported. Dexamethasone-treated patients had significantly less nausea and vomiting (P = .0001) and less pain (P = .008); however, no differences were noted in subjective voice analyses (P = .693).…”

Efectividad De Anestesia De Plexo Cervical Superficial Preoperatorio Para Control De Dolor Postoperatorio en Cirugía De Tiroides

“…Los vómi-tos pueden aumentar el riesgo de hematoma a tensión de cuello, la complicación más temida durante el postoperatorio de una tiroidectomía 5 . Con el objetivo de realizar analgesia preventiva en una tiroidectomía se plantea el uso de un bloqueo de plexo cervical superficial.…”