Diabetes Mellitus

Teramoto, Tamio; Sasaki, Jun; Ishibashi, Shun; Birou, Sadatoshi; Daida, Hiroyuki; Dohi, Seitaro; Egusa, Genshi; Hiro, Takafumi; Hirobe, Kazuhiko; Iida, Mami; Kihara, Shinji; Kinoshita, Makoto; Maruyama, Chizuko; Ohta, Takao; Okamura, Tomonori; Yamashita, Shizuya; Yokode, Masayuki; Yokote, Koutaro

doi:10.5551/jat.19349

Cited by 16 publications

(4 citation statements)

References 72 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Systolic and diastolic blood pressures were measured in an examination room, and patients were considered to have hypertension if they had systolic blood pressure ≥130 mmHg, diastolic blood pressure ≥80 mmHg, or were using oral antihypertensives [24]. Patients were considered to have dyslipidemia if they had triglycerides ≥150 mg/dL, high-density lipoprotein cholesterol <40 mg/dL, low-density lipoprotein cholesterol ≥120 mg/dL (≥100 mg/dL in the case of a coronary artery disease), or used oral hypolipidemic drugs [25]. Diabetic retinopathy was diagnosed by an ophthalmologist.…”

Section: Methodsmentioning

confidence: 99%

Development of a Japanese version of the SARC-F for diabetic patients: an examination of reliability and validity

et al. 2016

View full text Add to dashboard Cite

show abstract

Section: Methodsmentioning

confidence: 99%

Development of a Japanese version of the SARC-F for diabetic patients: an examination of reliability and validity

et al. 2016

View full text Add to dashboard Cite

show abstract

“…HbA1c <7% is known as a treatment target with respect to diabetic complications from the guidelines [ 1 14 ]. In this study, 60.2% of patients with moderate diabetes reached this level, indicating that DPP-4 inhibitors are effective in lowering glucose.…”

Section: Discussionmentioning

confidence: 99%

Predictive Factors for Efficacy of Dipeptidyl Peptidase-4 Inhibitors in Patients with Type 2 Diabetes Mellitus

et al. 2015

View full text Add to dashboard Cite

BackgroundPredictive factors for the efficacy of dipeptidyl peptidase-4 (DPP-4) inhibitors for lowering glycosylated hemoglobin (HbA1c) remain unclear in patients with type 2 diabetes mellitus. The aim of this study is therefore to clarify predictive factors of the efficacy of DPP-4 inhibitors for lowering HbA1c after 12 months of treatment.MethodsA total of 191 consecutive type 2 diabetic patients (male sex 55%, mean age, 68.3±35.8 years), who had been treated with DPP-4 inhibitors for 12 months, were enrolled in this study and evaluated retrospectively.ResultsAfter 12 months of DPP-4 inhibitor treatment, random blood glucose level, and HbA1c level, decreased from 167±63 to 151±49 mg/dL (P<0.01), and from 7.5%±1.3% to 6.9%±0.9% (P<0.01) respectively, without severe side effects. Multiple regression analysis showed that predictors of DPP-4 inhibitor treatment efficacy in lowering HbA1c level after 12 months were a decrease in HbA1c level after 3 months of treatment, a high baseline HbA1c level, a low baseline body mass index, and the absence of coronary artery disease.ConclusionMost suitable candidates for treatment with DPP-4 inhibitors are diabetics who are not obese and do not have coronary artery disease. In addition, long-term efficacy of DPP-4 inhibitors can be predicted by decrement of HbA1c after 3 months of treatment.

show abstract

“…FBG, HbA1c, HDL-C, and TG were classified into two groups with the above cutoff values. TC ≥220 and LDL ≥ 140 were adopted as cutoff values according to the Japanese definition [ 15 ]. For the largest among the removed adenomas at the time of the initial colonoscopy, we determined the presence/absence of >20% villous components, grade of dysplasia (high/low), location, and size.…”

Section: Methodsmentioning

confidence: 99%

Metabolic factors accelerate colorectal adenoma recurrence

Taniguchi¹,

Higurashi

Uchiyama³

et al. 2014

BMC Gastroenterol

View full text Add to dashboard Cite

BackgroundMetabolic factors have been reported to increase the prevalence of colorectal adenomas, however, whether metabolic factors might also accelerate the recurrence after removal of adenomas has not yet been discussed. In this retrospective multicenter study, we clarified the risk factors for adenoma recurrence focusing on metabolic factors.MethodsWe analyzed the medical records of 43,195 patients who had undergone colonoscopy between January 2005 and December 2011 at 5 hospitals in Japan. Of these, the data of 1111 patients who had undergone removal of adenomas at the first screening colonoscopy, and then been followed up by colonoscopy 1 year and 2 years later were analyzed.ResultsThe following 8 factors were demonstrated with a multivariate analysis as being associated with colorectal adenomas recurrence: for adenoma-related factors, 5 factors (villous features, grade of dysplasia, location and size of the largest removed adenoma, and number of the removed adenomas) were identified; for metabolic factors and other factors, 3 factors (age, body mass index (BMI), and fasting blood glucose (FBG)) were identified. A risk score (0–10 points) was developed based on these 8 factors. The risk of adenoma recurrence increased as the risk score increased. When the risk score was ≥3 (3–10) points, the odds ratio relative to <3 (0–2) points was 7.07 (95% CIs 5.30–9.43).ConclusionsIn addition to adenoma-related factors (villous features, grade of dysplasia, location, size and number), 3 factors (age, BMI and FBG) were demonstrated to influence the recurrence rate of colorectal adenoma. When the risk score was ≥3, the risk of recurrence was significantly elevated.

show abstract

Diabetes Mellitus

Cited by 16 publications

References 72 publications

Development of a Japanese version of the SARC-F for diabetic patients: an examination of reliability and validity

Development of a Japanese version of the SARC-F for diabetic patients: an examination of reliability and validity

Predictive Factors for Efficacy of Dipeptidyl Peptidase-4 Inhibitors in Patients with Type 2 Diabetes Mellitus

Metabolic factors accelerate colorectal adenoma recurrence

Contact Info

Product

Resources

About