“…However, evaluation has been carried out with N Latex in patients with renal impairment (without myeloma) where, unlike Seralite® and Freelite®, an adapted κ:λ ratio renal reference range was found not to be required [20]. Good clinical concordance has been shown between the different sFLC methods previously [14,15,17]. However, it is essential to remember that assays cannot be used interchangeably as they quantitate sFLC levels in different ways, particularly monoclonal FLCs [14,15,20,21].…”