Diagnostic Accuracy of Screening Tests and Treatment for Post–Acute Coronary Syndrome Depression

Nieuwsma, Jason A.; Williams, John W; Namdari, Natasha; Washam, Jeffrey B.; Raitz, Giselle; Blumenthal, James A.; Jiang, Wei; Yapa, Roshini; McBroom, Amanda J; Lallinger, Kathryn R; Schmidt, Robyn; Kosinski, Andrzej S.; Sanders, Gillian D

doi:10.7326/m17-1811

Cited by 20 publications

(15 citation statements)

References 44 publications

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“…Effective psychotherapeutic and psychopharmacological treatment options are available. In contrast to patients with depression without somatic comorbidity, psychotherapeutic and psychopharmacological treatments have only modest effects on depression severity among patients with depression and cardiac diseases [ 3 – 6 ]. To target and individualize psychological treatments, research is required to investigate the effects of individual factors on treatment [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

“…In addition, understanding these complex depression related illness representations in patients with chronic physical diseases is important, because they appear to impact self-management [ 27 ], could have implications for engagement with depression screening [ 31 ] and, thus, for the provision of care [ 27 ]. With respect to modest effects of depression treatment among patients with heart diseases [ 3 – 6 ], the investigation of depression related illness beliefs appears to be promising.…”

Section: Introductionmentioning

confidence: 99%

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Illness beliefs about depression among patients seeking depression care and patients seeking cardiac care: an exploratory analysis using a mixed method design

et al. 2018

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BackgroundTreatment of depression in cardiac patients is difficult. Patients’ illness beliefs regarding depression are associated with outcomes. The aim of the mixed-methods study was to test whether patients in routine care for depression differ from patients with depression in routine care for cardiac diseases regarding illness beliefs about depression.MethodsA consecutive sample of n = 217 patients with depressive disorder was recruited from routine care for depression (N = 148) and routine care for cardiac diseases (N = 69). Beliefs about depression were measured by the Brief-Illness Perception Questionnaire. Causal beliefs were categorized using qualitative methods. To investigate differences regarding other illness beliefs, we performed an ANCOVA controlling for sociodemographic and clinical differences by propensity score matching.ResultsPatients in routine care for cardiac diseases attributed their depression more often to physical illnesses (48% vs. 16%) and less often to their self (30% vs. 47%), problems at work (25% vs. 35%), childhood (25% vs. 30%), and negative life events (19% vs. 25%) in contrast to patients in routine care for depression. Patients in routine care for cardiac diseases reported beliefs of lower disability, burden, and treatment-control and of higher self-control in contrast to patients in routine care for depression.ConclusionsIllness beliefs especially causal beliefs differ between patients in routine care for cardiac diseases and routine care for depression. Future research should investigate effects of these illness beliefs. We recommend exploring patients’ illness beliefs about depression in routine care for cardiac diseases and routine care for depression.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Illness beliefs about depression among patients seeking depression care and patients seeking cardiac care: an exploratory analysis using a mixed method design

et al. 2018

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“…Patients with CAD have a higher frequency of depression, and medication nonadherence in the context of failed antidepressant therapy can lead to poor outcome for CAD as well. In a recent systematic review of antidepressant efficacy in patients with CAD, current prescribing strategies are only 'moderately efficacious' [18]. Yet uncontrolled depression is an independent risk factor for CAD [19,20].…”

Section: Discussionmentioning

confidence: 99%

CYP2C19 Genotype, Physician Prescribing Pattern, and Risk for Long QT on Serotonin Selective Reuptake Inhibitors

et al. 2019

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To examine the impact of CYP2C19 genotype on selective serotonin reuptake inhibitor (SSRI) prescribing patterns. Patients & methods: Observational cohort containing 507 unique individuals receiving an SSRI prescription with CYP2C19 genotype already in their electronic medical record. Genotype was distributed as follows: n = 360 (71%) had no loss of function alleles, 136 (26.8%) had one loss of function allele and 11 (2.2%) had two loss of function alleles. Results & conclusion: For poor metabolizers exposed to sertraline, citalopram or escitalopram, providers changed prescribing patterns in response to alerts in the electronic medical record by either changing the drug, changing the dose or monitoring serial EKGs longitudinally. For intermediate metabolizers exposed to sertraline, citalopram or escitalopram, no alert was needed (mean QTc = 440.338 ms [SD = 31.1273] for CYP2C19*1/*1, mean QTc = 440.371 ms [SD = 29.2706] for CYP2C19*1/*2; p = 0.995).

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“…173 Although there is no direct evidence that screening for depression leads to improved outcomes in cardiovascular populations, depression has been linked with increased morbidity and mortality, poorer risk-factor modification, lower rates of cardiac rehabilitation, and reduced quality of life. [174][175][176] Therefore, the American Heart Association 2008 Advisory on Depression and Coronary Heart Disease emphasized the importance of assessing depression in cardiac patients with the goal of targeting those most in need of treatment and support services. 177 Jha et al, published a State of the Art Review of Screening and Management of Depression in Patients with Cardiovascular Disease to reinforce screening and best practices in medicine.…”

Section: Treatment Of Depression In Primary and Secondary Prevention Of Cvdmentioning

confidence: 99%

The Canadian Women’s Heart Health Alliance Atlas on the Epidemiology, Diagnosis, and Management of Cardiovascular Disease in Women — Chapter 4: Sex- and Gender-Unique Disparities: CVD Across the Lifespan of a Woman

et al. 2022

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This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

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Diagnostic Accuracy of Screening Tests and Treatment for Post–Acute Coronary Syndrome Depression

Abstract: Agency for Healthcare Research and Quality (PROSPERO: CRD42016047032).

Cited by 20 publications

References 44 publications

Illness beliefs about depression among patients seeking depression care and patients seeking cardiac care: an exploratory analysis using a mixed method design

Illness beliefs about depression among patients seeking depression care and patients seeking cardiac care: an exploratory analysis using a mixed method design

CYP2C19 Genotype, Physician Prescribing Pattern, and Risk for Long QT on Serotonin Selective Reuptake Inhibitors

The Canadian Women’s Heart Health Alliance Atlas on the Epidemiology, Diagnosis, and Management of Cardiovascular Disease in Women — Chapter 4: Sex- and Gender-Unique Disparities: CVD Across the Lifespan of a Woman

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