Diagnostic and Therapeutic Challenges

Evaluation of focal choroidal excavation in the macula using swept-source optical coherence tomography

“…Previous reports have reported non-specific pigmentary changes and yellow spots correlating to the area of FCE on fundal examination, but none reported the direct visualization of the excavation clinically. [1][2][3]5,8 Of our three patients with no co-existing pathology at the site of FCE, RPE mottling at the area of excavation was seen in two eyes, whereas no abnormality was detected in the remaining eye. In these eyes, observation over time did not show any worsening of symptoms or clinical appearance on fundal examination.…”

“…What was known before K Focal choroidal excavation is a new entity that was first described by Jampol et al 1 It was defined as an area of macular choroidal excavation detected on an SD-OCT scan without evidence of a posterior staphyloma or scleral ectasia, in a patient lacking a history of trauma, posterior uveitis, retinal or choroidal vascular disease, or prior retinal or choroidal infection. As of today, etiology of FCE remains debated.…”

Focal choroidal excavation in patients with central serous chorioretinopathy

“…1 Clinically, FCE appears as a small localized lesion with focal pigmentary changes in fundus examination. The exact etiology of FCE remains unknown and is postulated to be an idiopathic congenital condition.…”

Efficacy of Simultaneous Usage of Bevacizumab and Silicone Oil Injection After Vitrectomy in Diabetic Tractional Retinal Detachment

“…While, in our study no vitreous hemorrhage was detected postoperatively. The precise mechanism of early postoperative VH cutback and intraoperative bleeding following IVB injection in our series is not clear, however, a new vessel constriction secondary to attenuation of the caliber of the normal retinal vessels (20), reduction of intraocular vascular endothelial growth factor (21) and lessening of the retinal circulation were demonstrated after IVB injection (22,23) that may explain our finding.…”