Diagnostic des causes de complication du diabète et des méthodes de prévention à Bobo-Dioulasso, au Burkina Faso

Koevi, Kka; Millogo, Vinsoun; Ouédraogo, M.; Ouedraogo, GA

doi:10.4314/ijbcs.v8i6.30

Cited by 4 publications

(6 citation statements)

References 8 publications

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“…Furthermore, Saleem and Basha (2010) reported that flavonoids could inhibit the low-density lipoprotein (LDL) cholesterol oxidation and prevent atherosclerosis and decrease the cardiovascular disease risk. Since there is positive correlation between diabetes and cardiovascular disease (Koevi et al, 2014), this probably explains why the diabetes patients refer to Combretum molle and Pericopsis laxiflora. According to Ajibesin (2011), several reasons may explain the utilization of the plant materials used in the treatment of diseases.…”

Section: Discussionmentioning

confidence: 99%

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Phytochemical analysis and antioxidant activities of Combretum molle and Pericopsis laxiflora

Koevi¹,

Millogo²,

Fokou³

et al. 2016

Int. J. Bio. Chem. Sci

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In Burkina Faso as in several African countries, diabetes is becoming a very serious disease and public concern. Patients use both drugs and plants for treatment. Thus, Combretum molle and Pericopsis laxiflora have been identified as plants used in Burkina Faso for the treatment of that disease. The aim of the study was to assess phytochemical components and antioxidant activities of those plants in order to highlight why diabetes patients refer to them. The phytochemical analysis of water, ash quantification and screening were done using the standard methods; the antioxidant activities of the ethanolic extract against 2, 2-diphenyl-1picryl-hydrazyl (DPPH), nitric oxide (NO) and hydroxyl radical were performed using colorimetric or spectrophotometric methods. The Inhibitory Concentration (IC) was determined using GraphPad Prism version 5. The results showed 6.76±0.076% and 7.52±0.015% of water contents in Combretum molle and Pericopsis laxiflora, respectively. The ash content was 3.41±0.35% for Combretum molle and 3.87±0.15% for Pericopsis laxiflora. The screening revealed the presence of tannins, phenolic compounds, flavonoids and saponins in both plant materials. However, alkaloids were found in Pericopsis laxiflora and hydrolysables tannins and heterosides cardiotonics in Combretum molle. The IC 50 for the extract plant of Combretum molle was 42 µg/mL and that of the Pericopsis laxiflora was 44.15 µg/mL for DPPH radical. The antioxidant effect of the extract plant of Combretum molle was 216 µg/mL and the extract plant of Pericopsis laxiflora was 225 µg/mL on the nitric oxide radical. It was concluded that the presence of tannins, flavonoids, phenolic compounds, saponin, alkaloids and cardiotonic heterosides, explains why traditional medicine uses both plants together to treat certain diseases. However, further investigations of the pharmacological potential for diabetes treatment are needed.

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Section: Discussionmentioning

confidence: 99%

“…In Burkina Faso, as in several African countries, diabetes is becoming a very serious disease and a public concern. Recently, it was found that many people were in the risk of diabetes when they reached age 40 and 66% of diabetes patients were women (Koevi et al, 2014). Other studies showed two types of treatments people refer to.…”

Section: Introductionmentioning

confidence: 99%

Phytochemical analysis and antioxidant activities of Combretum molle and Pericopsis laxiflora

Koevi¹,

Millogo²,

Fokou³

et al. 2016

Int. J. Bio. Chem. Sci

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“…In Burkina Faso, there is a progression of diabetes mainly due to ignorance, new and bad eating habits (Koevi et al, 2014). In 2015, prevalence rate of diabetes was 8.5% (10.4% among women and 6.9% among men) in urban areas of Ouagadougou (Millogo et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

“…In 2015, prevalence rate of diabetes was 8.5% (10.4% among women and 6.9% among men) in urban areas of Ouagadougou (Millogo et al, 2015). The prevalence is linked to factors such as obesity, poor diet, low physical activity, gender and age (Koevi et al, 2014;Millogo et al, 2015).There is complexity in the drug treatment of diabetes due to its progressive nature and association with other cardiovascular risk factors such as hypertension, obesity, smoking, stroke, kidney failure, leg amputation, vision loss and nerve damage. Modern management of disease, particularly constraining, from insulin injections (type 1 diabetes) to anti-diabetic drugs (type 2 diabetes) and requires lifelong treatment and regular follow-up (Gbekley et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

Consensus level in the traditional management of diabetes and chemical potentiality of plants from north Sudanese, Burkina Faso

Compaoré¹,

Belemnaba²,

Koala³

et al. 2020

J. Med. Plants Res.

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Diabetes, has become a public health problem whose prevalence is increasing in subsahelian Africa. The present study aimed to determine the consensus level of plant use and their antidiabetic potentiality. Thus, a semi-structured interview carried out from May 2014 to April 2018 with 120 traditional healers allowed retaining nine species after selection according to the frequency of citation and the bibliographic review: Crescentia cujete L., Ficus ingens (Miq.) Miq. Ficus platyphylla Delile, Lannea acida A. Rich., Balanites aegyptiaca (L.) Delile, Daniellia oliveri (Rolfe) Hutch. & Dalziel, Feretia apodanthera Delile, Cassia italica (Mill.) Lam. ex F.W. Andrews and Boscia angustifolia A. Rich. Phytochemical screening of methanolic and aqueous extracts was performed by high performance thin layer chromatography and the total flavonoids, hydrolyzable and condensed tannins were determined by spectrophotometer method. Results showed that thirty-seven, fifty-five and sixty-five species were inventoried in the provinces of Bazega, Zounweogo and Sanmatenga respectively but the Informant Consensual Factor related to the plant use remains low (FIC<50%). Notwithstanding this, phytochemical screening of plant extracts showed the presence of flavonoids and tannins. The highest flavonoids and hydrolysable tannins content were obtained with Cassia italica (Mill.) Lam. ex F.W. Andrews methanolic extracts (11.03±0.07 mg EQ/100 g dry matter and 34.82±0.14 mg ETA /100 g dry matter respectively). The best condensed tannins content was noted with Lannea acida A. Rich. methanolic extract (543.94±18.67 mg ETA /100 g dry matter). These results constitutes a scientific basis that can be directed towards a pharmacological and toxicological investigation.

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“…Ce n'est donc pas une maladie unique mais plutôt un ensemble d'anomalies métaboliques et pathologiques, avec une variété de causes environnementales et héréditaires (Jansse et al, 2007). L'âge, le sexe, la profession, le revenu et l'antécédent familial représenteraient les facteurs de risques d'apparition du diabète (Koevi et al, 2014). Le diabète est l'une des maladies non transmissibles les plus répandues dans le monde, avec un effectif de patients diabétiques en 2014 qui avoisinait 422 millions de personnes (OMS, 2016).…”

Section: Introductionunclassified

Aspects épidémiologiques du diabète de type 1 à la banque d’insuline de Cotonou (Bénin)

Fagbemi¹,

Azonbakin²,

Adjagba³

et al. 2017

Int. J. Bio. Chem. Sci

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RESUMELe diabète sucré, bien qu'étant considéré comme une maladie des pays riches, constitue de plus en plus une préoccupation majeure dans les pays en développement et particulièrement en Afrique subsaharienne. L'objectif de cette étude était de déterminer les caractéristiques sociodémographiques, d'évaluer la fréquence du diabète de type 1 (DT1) et de calculer le taux de mortalité chez les diabétiques de type 1 ayant consultés à la Banque d'Insuline de Cotonou de janvier 1996 à décembre 2015. Une recherche bibliographique initiale a été menée début septembre 2012 et mise à jour systématiquement jusqu'à fin mars 2017. Des fiches d'enquêtes ont été préétablis pour recueillir dans un premier temps des informations contenues dans les dossiers des patients DT1 en général et dans un second temps des informations relatives aux patients DT1 qui ont pu être contactés. Au total, 12000 dossiers ont été étudiés dont 103 dossiers de patients DT1. La fréquence du DT1 retrouvée est de 0,9%. Un taux de mortalité de 34% a été relevé dans le groupe des patients diabétiques de type 1 avec une part de mortalité de 54,3% chez les hommes et 45,7% chez les femmes. © 2017 International Formulae Group. All rights reserved.Mots clés : Caractéristiques sociodémographiques, fréquence, mortalité, diabète de type 1, Bénin. Epidemiological aspects of type 1 diabetes in the Insulin center of Cotonou (Benin) ABSTRACTThe diabetes mellitus, long time considered as a disease of the developed countries, is more and more becoming a major concern in developing countries and particularly in sub-Saharan Africa. The aim of this study was to determine the sociodemographic characteristics, to estimate the frequency of the type 1 diabetes (T1D) among all type of diabetes and to calculate the mortality rate in the patients with T1D registered at the "insulin center" of Cotonou from January 1996 to December 2015. Firstly, a bibliographical research was effectuated from September, 2012 and regularly updated until March 2017. Investigations sheets were pre-K. A. FAGBEMI et al. / Int. J. Biol. Chem. Sci. 11(3): 1085-1095, 2017 1086 established firstly to collect data contained in the files of all the T1D patients, and secondly, data concerning the only T1D patients who are contacted during the study. At all, 12000 patients' files were studied and 103 files of patients suffering from T1D. The frequency of the T1D at the "insulin center" of Cotonou was 0.9%. The mortality rate was 34% in the group of the T1D patients with 54.3% belonging to men and 45.7% to the women.

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Diagnostic des causes de complication du diabète et des méthodes de prévention à Bobo-Dioulasso, au Burkina Faso

Cited by 4 publications

References 8 publications

Phytochemical analysis and antioxidant activities of <i>Combretum molle</i> and <i>Pericopsis laxiflora</i>

Phytochemical analysis and antioxidant activities of <i>Combretum molle</i> and <i>Pericopsis laxiflora</i>

Consensus level in the traditional management of diabetes and chemical potentiality of plants from north Sudanese, Burkina Faso

Aspects épidémiologiques du diabète de type 1 à la banque d’insuline de Cotonou (Bénin)

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