2012
DOI: 10.1016/s0104-4230(12)70236-1
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Diagnostic methods in sepsis: the need of speed

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Cited by 21 publications
(12 citation statements)
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“…On the other hand, procalcitonin (PCT) plays a pivotal role in the diagnosis of sepsis as well as in the prescription of effective medications. However, the mechanism of sepsis is complex, which renders PCT as a poor independent indicator for the differential diagnosis of infections . In recent years, studies have shown that heparin binding protein (HBP) can also be used as an indirect biomarker for the early diagnosis of sepsis, because it positively correlated with the PCT level .…”
Section: Introductionmentioning
confidence: 99%
“…On the other hand, procalcitonin (PCT) plays a pivotal role in the diagnosis of sepsis as well as in the prescription of effective medications. However, the mechanism of sepsis is complex, which renders PCT as a poor independent indicator for the differential diagnosis of infections . In recent years, studies have shown that heparin binding protein (HBP) can also be used as an indirect biomarker for the early diagnosis of sepsis, because it positively correlated with the PCT level .…”
Section: Introductionmentioning
confidence: 99%
“…The onset of sepsis can occur with all its specific symptoms or, on the contrary, the clinical symptoms can be difficult to detect as they can be masked by underlying disease. Once there is a query of organ infection, one of the main goals is to identify the pathogen [5,6]. Typically, bacteriological diagnosis is made by cultures or Gram staining and microscopic identification.…”
Section: Introductionmentioning
confidence: 99%
“…54 If such a dipstick could be developed for a rapid urinary analysis, there are high-impact implications in diverse settings ranging from a busy ED to rural community-type settings with little access to laboratory or clinical analytical systems. 55…”
Section: Summary and Future Directionsmentioning
confidence: 99%