Diagnostic Performance of Prostate Imaging Reporting and Data System Version 2 for Detection of Prostate Cancer: A Systematic Review and Diagnostic Meta-analysis

Woo, Sungmin; Suh, Chong Hyun; Kim, Sang-Youn; Cho, Jeong Yeon; Kim, Seung Hyup

doi:10.1016/j.eururo.2017.01.042

Cited by 267 publications

(197 citation statements)

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“…Multiparametric MRI (mpMRI) is used to guide re-biopsy in such patients and has been shown to outperform systematic TRUS biopsy for lesion detection [5]. However, studies report considerable variation in MRI performance, with sensitivity and specificity ranging from 73-100% and 8-100%, respectively [6, 7], depending on composition of the study population, radiologist experience, technical issues, and the gold standard employed. Furthermore, specificity drops from 80% to 47% when including indeterminate lesions, i.e.…”

Section: Introductionmentioning

confidence: 99%

“…Furthermore, specificity drops from 80% to 47% when including indeterminate lesions, i.e. Prostate Imaging-Reporting and Data System (PI-RADS) score 3 lesions in addition to score 4-5 [6, 7]. This highlights the need for improvement of existing sequences, or use of additional functional sequences, with the most recent version of the PI-RADS guidelines strongly supporting the continued development of further novel MRI sequences [8].…”

Section: Introductionmentioning

confidence: 99%

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Diagnostic evaluation of magnetization transfer and diffusion kurtosis imaging for prostate cancer detection in a re-biopsy population

et al. 2017

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ObjectiveTo evaluate diffusion kurtosis imaging (DKI) and magnetisation transfer imaging (MTI) compared to standard MRI for prostate cancer assessment in a re-biopsy population.MethodsThirty-patients were imaged at 3 T including DKI (Kapp and Dapp) with b-values 150/450/800/1150/1500 s/mm2 and MTI performed with and without MT saturation. Patients underwent transperineal biopsy based on prospectively defined MRI targets. Receiver-operating characteristic (ROC) analyses assessed the parameters and Wilcoxon-signed ranked test assessed relationships between metrics.ResultsTwenty patients had ≥ 1 core positive for cancer in a total of 26 MRI targets (Gleason 3+3 in 8, 3+4 in 12, ≥ 4+3 in 6): 13 peripheral (PZ) and 13 transition zone (TZ). The apparent diffusion coefficient (ADC) and Dapp were significantly lower and the Kapp and MT ratio (MTR) significantly higher in tumour versus benign tissue (all p ≤ 0.005); ROC values 0.767-1.000. Normal TZ had: lower ADC and Dapp and higher Kapp and MTR compared to normal PZ. MTR showed a moderate correlation to Kapp (r = 0.570) and Dapp (r = -0.537) in normal tissue but a poor correlation in tumours. No parameter separated low-grade (Gleason 3+3) from high-grade (≥ 3+4) disease for either PZ (p = 0.414-0.825) or TZ (p = 0.148-0.825).ConclusionADC, Dapp, Kapp and MTR all distinguished benign tissue from tumour, but none reliably differentiated low- from high-grade disease.Key Points• MTR was significantly higher in PZ and TZ tumours versus normal tissue • K app was significantly lower and D app higher for PZ and TZ tumours • There was no incremental value for DKI/MTI over mono-exponential ADC parameters • No parameter could consistently differentiate low-grade (Gleason 3+3) from high-grade (≥ 3+4) disease • Divergent MTR/DKI values in TZ tumours suggests they offer different functional information Electronic supplementary materialThe online version of this article (10.1007/s00330-017-5169-1) contains supplementary material, which is available to authorized users.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Diagnostic evaluation of magnetization transfer and diffusion kurtosis imaging for prostate cancer detection in a re-biopsy population

et al. 2017

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“…Woo ve ark. [9], 21 çalışmayı (3857 hasta) dahil ettikleri meta-analizin sonuçlarına göre, PIRADSv2'nin prostat kanserini tespit etmede havuzlanmış duyarlılığını %89 ve öz-güllüğünü %73 olarak bildirmektedir. Bu meta-analizde teknik yönden yapılan değerlendir-mede; endorektal koil kullanımının istatistiksel olarak anlamlı bir faktör olmadığı ve dahası 3 T'nin 1,5 T'ye klinik olarak anlamlı üstünlüğü olmadığı bildirilmektedir.…”

Section: Kaç Tesla? Hangi Koil Tercih Edilmeli?unclassified

1,5 Tesla ile Prostat MRG

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“…Although these results seem very promising, there is significant variability in the published studies [11], depending of the number of cases and the experience of the radiologist. Lower volume centers report a negative predictive value of mpMRI as low as 63% [12] and a moderate rate of interreader agreement, even after the implementation of PI-RADS version 2 (kappa=0.478) [13].…”

Section: Introductionmentioning

confidence: 96%

Prostate ultrasound: back in business!

et al. 2017

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The use of grey scale prostate ultrasound decreased after the implementation of magnetic resonance imaging (MRI) for the diagnosis and evaluation of prostate cancer. The new developments, such as multiparametric ultrasound and MRI-ultrasound fusion technology, renewed the interest for this imaging method in the assessment of prostate cancer. The purpose of this paper was to review the current role of prostate ultrasound in the setting of these new applications. A thorough reevaluation of the selection criteria of the patients is required to assess which patients would benefit from multiparametric ultrasound, who wouldbenefit from multiparametric MRI or the combination of both to assist prostate biopsy in order to ensure the balance between overdiagnosis and underdiagnosis of prostate cancer.

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Diagnostic Performance of Prostate Imaging Reporting and Data System Version 2 for Detection of Prostate Cancer: A Systematic Review and Diagnostic Meta-analysis

Cited by 267 publications

References 39 publications

Diagnostic evaluation of magnetization transfer and diffusion kurtosis imaging for prostate cancer detection in a re-biopsy population

Diagnostic evaluation of magnetization transfer and diffusion kurtosis imaging for prostate cancer detection in a re-biopsy population

1,5 Tesla ile Prostat MRG

Prostate ultrasound: back in business!

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