Diagnostic tests in obstetrics: A method for improved evaluation

Richardson, Douglas K.; Schwartz, Jacob; Weinbaum, Paul J.; Gabbe, Steven G.

doi:10.1016/s0002-9378(85)80031-4

Cited by 89 publications

(38 citation statements)

References 13 publications

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“…We used the method of Bickel and Docksum [12] to calculate the risk of overlooking an endometrial abnormality if a certain endometrial thickness was used as the cut-off limit. A receiver-operator characteristic curve was drawn to determine which cut-off level of endometrial thickness best discriminated between normal and abnormal endometrium [13] .…”

Section: Discussionmentioning

confidence: 99%

Transvaginal Ultrasonography of the Endometrium in Postmenopausal Japanese Women

Tsuda

Nakamura

Inoue

et al. 2005

Gynecol Obstet Invest

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Aims: To determine the cut-off level of endometrial thickness for detecting endometrial disease on a large scale of screening and to examine the usefulness of transvaginal ultrasonography (TVS) for endometrial disease screening in asymptomatic postmenopausal Japanese women. Methods: The study involved 1,400 postmenopausal women in whom endometrial thickness was measured with TVS, and then compared with the histopathological diagnosis of endometrial specimens. Results: The prevalence of endometrial disease in asymptomatic and symptomatic cases was 2.3 and 21%. In symptomatic cases, at a cut-off limit of 3 mm for endometrial thickness, the sensitivity for detecting endometrial disease was 94%, specificity 70% and positive predictive value 46%. With an endometrial thickness ≤3 mm, the probability that endometrial disease would be overlooked was 0.025.In asymptomatic cases, the corresponding figures at a cut-off limit of 3 mm were 90, 84, 12% and 0.003. Conclusions: TVS does not appear to be an effective screening method in asymptomatic postmenopausal Japanese women because of the low prevalence of endometrial disease in this population. We recommend a normal cut-off level for endometrial thickness of 4 mm in symptomatic postmenopausal Japanese women.

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Section: Discussionmentioning

confidence: 99%

Transvaginal Ultrasonography of the Endometrium in Postmenopausal Japanese Women

Tsuda

Nakamura

Inoue

et al. 2005

Gynecol Obstet Invest

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“…Receiver operating characteristic curves (ROC curves) were generated with the Statistical Package for the Social Sciences (SPSS Inc., Chicago, IL, USA, 1989 -99) and GraphROC for Windows (downloaded from http:// members.tripod.com/refstat/). These curves were used to determine if cut-off values other than those suggested in the original publications 4,5 had better diagnostic properties 11 . The GraphROC for Windows software enabled statistical testing of ROC curves by comparing the areas under the graphs 12 .…”

Section: Pelvic Tumorsmentioning

confidence: 99%

Comparison of ‘pattern recognition’ and logistic regression models for discrimination between benign and malignant pelvic masses: a prospective cross validation

Valentin

Hagen

Tingulstad

et al. 2001

Ultrasound in Obstet & Gyne

204

142

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Results Pattern recognition performed better than the two logistic regression models (sensitivity around 85%, specificity around 90%). Using a risk of malignancy of > 50% to indicate malignancy (as suggested in the original publications), the sensitivity of the Tailor model was 69% and the specificity 88% (n = 133). The corresponding values for the Timmerman model were 62% and 79% (n = 82). The receiver operating characteristics curves showed the two logistic regression models to have similar diagnostic properties (area under the curve, 0.87 vs. 0.84; P = 0.25; n = 79).The diagnostic performance of the mathematical models was much poorer in this study than in those in which the models had been created. Conclusion

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“…The application of the regression equation to data from each woman gave the probability for that woman to go into spontaneous labor > 24 h or > 48 h, and to deliver > 48 h or > 60 h, the estimated probability ranging from 0 to 1. Receiver-operating characteristics (ROC) curves 14 were drawn for each diagnostic test (i.e. Bishop score, cervical length and the logistic regression models) to evaluate its diagnostic ability.…”

Section: Discussionmentioning

confidence: 99%

“…The statistical significance of a difference in the area under the ROC curve between the different diagnostic tests was determined as described by Hanley and McNeil 15,16 using a customized computer program written in MATLAB (Version 6.5.0.180913a Release 13) designed by one of the co-authors (F. de S.). The ROC curves were also used to determine the mathematically best cut-off value for each diagnostic test, the best cut-off value being defined as the one corresponding to the point on the ROC curve situated furthest away from the reference line 14 . The sensitivity, false-positive rate, and positive and negative likelihood ratios of the mathematically best cut-off values with regard to predicting onset of labor > 24 h and > 48 h, and delivery > 48 h and > 60 h were also calculated.…”

Section: Discussionmentioning

confidence: 99%

Three‐dimensional ultrasound assessment of the cervix for predicting time to spontaneous onset of labor and time to delivery in prolonged pregnancy

Rovas

Sladkevicius

Strobel

et al. 2006

Ultrasound in Obstet & Gyne

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Diagnostic tests in obstetrics: A method for improved evaluation

Cited by 89 publications

References 13 publications

Transvaginal Ultrasonography of the Endometrium in Postmenopausal Japanese Women

Transvaginal Ultrasonography of the Endometrium in Postmenopausal Japanese Women

Comparison of ‘pattern recognition’ and logistic regression models for discrimination between benign and malignant pelvic masses: a prospective cross validation

Three‐dimensional ultrasound assessment of the cervix for predicting time to spontaneous onset of labor and time to delivery in prolonged pregnancy

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