Dialysis modality and sexual dysfunction in male patients

Tekkarismaz, Nihan; Tünel, Münevver; Özer, Cevahir

doi:10.1111/and.13735

Cited by 10 publications

(12 citation statements)

References 19 publications

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“…A recent meta-analysis reported that, of 7253 patients experiencing ED, 79% received HD, 71% received PD, and 59% were post-RT [122]. Seck et al [123] reported similar rates of ED in their study group of 70, as did Tekkarismaz et al [124] in their group of 51 HD and PD patients. Lai et al [76] reported ED in only 51.9% of their chronic PD cohort, but the authors suspect that this lower prevalence was due to the younger average age in their study group.…”

Section: Erectile Dysfunctionmentioning

confidence: 92%

“…Studies have also compared overall SD between different RRT modalities. Tekkarismaz et al [124] administered the HADS and the International Index of Erectile Function brief screening version (IIEF-5) to 51 dialyzing men and showed that the frequency of SD was 12.9% with HD and 30% with PD. Jung et al [89] conducted a mixed-methods cohort study of 989 male HD and PD patients using the kidney disease quality of life (KDQOL) SF TM 1.3 questionnaire, the Short Form health survey SF-36, and the BDI to assess QOL over 24 months over two RRT modalities.…”

Section: Erectile Dysfunctionmentioning

confidence: 99%

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Multifaceted Sexual Dysfunction in Dialyzing Men and Women: Pathophysiology, Diagnostics, and Therapeutics

Chou

Kiebalo

Jagiello

et al. 2021

Life

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Patient survival continues to increase with the growing quality of dialysis and management of chronic kidney disease (CKD). As such, chronic therapy must include considerations of quality of life (QOL), and this includes the disproportionate prevalence of sexual dysfunction (SD) in this patient population. This review aims to describe the pathophysiological and the psychosocial causes of SD with regard to renal replacement therapy, particularly hemo- and peritoneal dialysis. The differences in its manifestation in men and women are compared, including hormonal imbalances—and therefore fertility, libido, and sexual satisfaction—the experience of depression and anxiety, and QOL. The impact of comorbidities and the iatrogenic causes of SD are described. This review also presents validated scales for screening and diagnosis of SD in CKD patients and outlines novel therapies and strategies for the effective management of SD. Increased prevalence of CKD invariably increases the number of patients with SD, and it is crucial for health care professional teams to become familiar with the clinical tools used to manage this sensitive and under-quantified field. As a known predictor of QOL, sexual function should become a point of focus in the pursuit of patient-centered care, particularly as we seek to achieve as “normal” a life as possible for individuals who receive dialysis.

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Section: Erectile Dysfunctionmentioning

confidence: 92%

Section: Erectile Dysfunctionmentioning

confidence: 99%

Multifaceted Sexual Dysfunction in Dialyzing Men and Women: Pathophysiology, Diagnostics, and Therapeutics

Chou

Kiebalo

Jagiello

et al. 2021

Life

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“…Генез статевої дисфункції при хронічній хворобі нирок (ХХН) є багатофакторним і має, насамперед, органічний характер, його продовжують активно вивчати як для встановлення особливостей та розкриття можливих патогенетичних ланок розвитку порушення сперматогенезу, так і для пошуку ефективних способів його корекції [1][2][3][4][5][6][7][8][9].…”

Section: вступunclassified

Effect of Quartzetin Treatment on Male Reproductive Function Under Conditions of Experimental Chronic Kidney Disease

Ukraіnska¹,

Kalеynikova²,

Voznesenska³

et al. 2022

Clin. and experim. pathol.

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The aim of the study – to evaluate the effect of five-fold treatment of quercetin on thereproductive function of males in mice under conditions of experimental chronic kidneydisease (EChKD), namely: 1) the number of sperm (sperm concentration (million/ml)) andthe number of abnormal sperm (%)); and provided that such males are mated with intactfemales to assess: 2) the values of embryonic mortality before and after implantation;3) the number of live fetuses per female mouse.Materials and methods. The study was performed in two series of experiments on maleand female mice with EChKD, a model of which was created by immunizing animals withkidney homogenate.Quercetin (QUR, Sigma, USA) (50 mg / kg) was administered intraperitoneally oncedaily, five times according to the immunization schedule after the fourth immunization(the last, 3 weeks after the start of the experiment).The first series of experiments is devoted to the study of: the number of sperm (spermconcentration (million/ml)) and the number of abnormal forms of sperm.Fertile qualities of males were evaluated in the second series of experiments, afterreplanting them to intact females. Pre- and post-implantation embryonic mortality andthe number of living fetuses per female mouse have been investigated.Results. The treatment of QUR does not change the number of sperm, pre- and postimplantation embryonic mortality and the number of live newborns (pups) compared tosuch values in the control. The treatment of QUR in experimental chronic kidney disease leads to a decrease (1.60 times) in the number of abnormal sperm and the magnitude(1.37 times) of postimplantation mortality of embryos, as well as an increase (1.47 times)in the number of live newborns (pups).Conclusions. The treatment of Quercetin in experimental chronic kidney disease leads toa decrease in the number of abnormal sperm and postimplantation mortality of embryos,as well as an increase in the number of live fetuses per female.Quercetin may be recommended for the correction of spermatogenesis in chronic kidneydisease and to clarify new strategies for its treatment.

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“…Выявлено, что СД чаще встречается у пациентов, получающих терапию перитонеальным диализом, чем у тех, кто получает терапию гемодиализом. Пожилой возраст, высокое кровяное давление, лечение железом, высокий уровень липидов и наличие депрессии были связаны с более высокой распространенностью СД [19].…”

Section: эректильная дисфункция у диализных больныхunclassified

Erectile dysfunction in kidney diseases: a review of the literature

Кадыров

Одилов

Саъдуллоев

2021

Androl. genit. hir.

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Analysis of the world literature shows that sexual dysfunction is a common problem in patients with chronic kidney disease, both men and women, and this problem for known reasons has not received proper recognition and attention among health professionals and organizers. The prevalence of erectile dysfunction among men with chronic kidney failure ranges from 70 to 86 %. Sexual disorders are associated with uremic effects, comorbidities, anemia, hormonal disorders, autonomic neuropathy, vascular disorders, hyperparathyroidism, hyperprolactinemia, drug side effects, and psychosocial factors. Erectile dysfunction has a serious impact on the quality of life and this strongly affects the social and family life of affected patients. Sexual dysfunction is more common in men and women with chronic kidney disease and cardiovascular disease. Patients on hemodialysis have better sexual function than those without it. Sexual dysfunction has a negative impact on the quality of life of patients with chronic kidney disease and therefore they need high-quality therapy, taking into account the stage, desire and ability of patients.

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Dialysis modality and sexual dysfunction in male patients

Abstract: Worldwide, chronic kidney disease (CKD) is reported to occur in more than 10% of the general population (Fugl-Meyer, Nilsson,

Cited by 10 publications

References 19 publications

Multifaceted Sexual Dysfunction in Dialyzing Men and Women: Pathophysiology, Diagnostics, and Therapeutics

Multifaceted Sexual Dysfunction in Dialyzing Men and Women: Pathophysiology, Diagnostics, and Therapeutics

Effect of Quartzetin Treatment on Male Reproductive Function Under Conditions of Experimental Chronic Kidney Disease

Erectile dysfunction in kidney diseases: a review of the literature

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