2021
DOI: 10.21037/shc-21-5
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Diameter versus volumetry: a narrative review on current recommendations to measure and monitor screening detected lung nodules

Abstract: Lung cancer (LC) is a leading cause of oncological death worldwide. Up to 70% of patients suffers from advanced disease at the time of diagnosis, which limits curative options. Early diagnosis of LC by means of low dose computed tomography (LDCT) has been proven effective by different LC screening (LCS) trials, which show a 20-30% mortality reduction in high-risk subjects. LDCT allows identification and longitudinal evaluation of pulmonary nodules (PNs), with subsequent stratification of LC risk based on their… Show more

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Cited by 2 publications
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“…LCS requires an adequate level of image quality as radiologists want to detect lung nodules when still small and characterize them as accurate as possible to provide appropriate work-up and/or follow-up management [ 3 , 4 ]. This way, participants with an early diagnosed lung cancer have a better prognosis with improved five-year survival rates and expanded eligibility for curative surgical treatment [ 3 , 23 , 24 ]. Per definition, pulmonary nodules are round opacities in the lung that are well or poorly defined and measure up to 3 cm in diameter [ 25 ].…”
Section: Introductionmentioning
confidence: 99%
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“…LCS requires an adequate level of image quality as radiologists want to detect lung nodules when still small and characterize them as accurate as possible to provide appropriate work-up and/or follow-up management [ 3 , 4 ]. This way, participants with an early diagnosed lung cancer have a better prognosis with improved five-year survival rates and expanded eligibility for curative surgical treatment [ 3 , 23 , 24 ]. Per definition, pulmonary nodules are round opacities in the lung that are well or poorly defined and measure up to 3 cm in diameter [ 25 ].…”
Section: Introductionmentioning
confidence: 99%
“…Even though there is a positive correlation between nodule size and malignancy, small nodules also have a likelihood of being malignant [23]. Nowadays, nodule management is primarily driven by nodule size, preferably determined by volumetry but diameter measurements are also possible [24,[26][27][28]. Therefore, accurate measurements of the size are essential.…”
Section: Introductionmentioning
confidence: 99%