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Introduction. Modern preventive measures of skin diseases aim to maintain the protective skin barrier. The area that comes in direct contact with the diaper becomes excessively wet, the corneous layer is damaged, which results in a weakened barrier function of the epidermis and the occurrence of an inflammatory process, diaper dermatitis.Aim. To study the clinical efficacy and safety of the use of disposable diapers and pull up pants in full-term and premature infants from birth to 1 year of age to prevent diaper dermatitis.Materials and methods. A total of 45 full-term and premature children under 1 year old with various diseases, including skin eruptions in the area covered by the diaper were included in the study. The proposed care products were used for 14 days on the strict condition that they would be reapplied after defecation and during hygiene procedures in a timely manner. The skin status was assessed visually by a paediatrician from Day 1 to 14 of the study using the M. Odio skin assessment scale.Results. The M. Odio scale evaluation of the skin around waist, buttocks, genitals, anal region, and inguinal folds in all children on Days 1, 7 and 14 showed 0 scores. No adverse events were reported during assessment of the skin status over 14 days of the use of care products.Discussion. The observations were consistent with the previously published data demonstrating that maintenance of the functional characteristics of the skin in the area covered by the diaper and exposed to faecal and urinary enzymes, elevated temperature and humidity prevented the development of diaper dermatitis and skin diseases.Conclusion. No signs of diaper dermatitis were detected in all 45 full-term and premature children under 1 year old, including children with various diseases, during 2 weeks of application of disposable Tanoshi Premium diapers and pull up pants in clinical practice. This fact proves the safety and good tolerance of disposable diapers by children under 1 year old provided that the skin care requirements were met. Tanoshi Premium diapers and pull up pants can be recommended for babies of different ages and body weights, including those with diaper dermatitis.
Background: It is of current importance to develop an algorithm for assessing chemical and physical safety of products for children and adolescents made with such innovative materials as organic cotton, bamboo, fibers and threads containing silver ions used for children’s underwear, materials impregnated with marigold extract for insoles of children’s footwear, and diapers from plant raw materials. The institute conducts testing and scientific substantiation of children’s goods made using innovative technologies. Objective: To assess safety of diapers made with innovative materials (ECO-diapers). Materials and methods: We conducted physicochemical, toxicological and organoleptic testing of 200 samples of medium size disposable baby ECO-diapers made with innovative materials. Results: The results of chemical and toxicological tests of ECO-diapers in a model aqueous environment showed that the formaldehyde concentration in aqueous extracts of the diaper samples ranged from 0.08 ± 0.020 to 0.1 mg/dm3; toxicity index values – from 74.1 to 89.1 %; pH – from 0.35 to 0.5 units, and the total phenolic content – from < 0.005 to 0.024 ± 0.002 mg/dm3, thus being within permissible limits. Measured concentrations of acetaldehyde, acrylonitrile, acetone, benzene, hexane, methyl and propyl alcohols, toluene, ethyl acetate, lead, arsenic, zinc, chromium were also below threshold values. Chemical testing of the samples of baby diapers in a model air environment with exposure duration of 4, 12, and 24 hours detected migration of chemicals already after four hours of exposure, which did not change following 12 and 24 hours. The value of water absorption capacity, which is one of the main indicators of functional benefit of diapers, ranged from 307.6 ± 30.8 g to 355.5 ± 35.5 g and significantly exceeded the established standard (not less than 240.0 g for medium size diapers) owing to the use of innovative materials in the production of ECO-diapers. Conclusions: Our findings demonstrate the necessity to develop special methodological approaches to measuring breathability of ECO- and traditional diapers, to regulate smell by including this organoleptic quality criterion in the list of safety requirements, and to limit exposure duration in a model air environment to four hours.
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