Diastereoselective Anomeric C(sp³)−H Cyclization Towards the Design of New Cyclophane‐Braced Glycopeptides

Abstract

Here we report a macrocyclization route towards the synthesis of glycophane peptides by a selective C‐H arylation of the anomeric bond. This approach demonstrates the power of Pd‐catalysis C‐H activation to access unusual cyclic peptides.