Die diffuse Onkozytose der Glandula Parotidea

Abstract

Diffuse hyperplastic oncocytosis of the parotid gland is an extremely rare benign disorder, complete excision of the tumor-like lesion is curative. In literature there has been no report of recurrence, malignant transformation or metastasizing illness.

Oncocytic lesion of parotid gland: A dilemma for cytopathologists

“…Indeed, solitary oncocytes appear most often as incidental findings in aging salivary tissue, with studies showing upto 80% presence in persons older than 70 years of age. [1]…”

“…Oncocytes are seen in various organs like salivary glands, thyroid, parathyroid, pituitary, nasal cavities, sinuses, ocular caruncle, lacrimal glands, buccal mucosa, eustachian tube, larynx, esophagus and organs like liver, pancreas, and kidney. [12] In salivary glands, they may be present in a plethora of conditions ranging from hyperplasia to overtly malignant lesions. Diagnosis by fine-needle aspiration cytology (FNAC) may be very difficult due to focal sampling of the lesion, as oncocytic change can occur in a large variety of neoplastic as well as non-neoplastic conditions.…”

Oncocytoma parotid gland

“…Indeed, solitary oncocytes appear most often as incidental findings in aging salivary tissue, with studies showing up to 80% presence in persons older than 70 years of age. [3] In our case also, the age of patient was 70 years which points toward the progressive degeneration of salivary epithelial cells which lead to oncocytic changes.…”

“…Oncocytes are seen in various organs such as salivary glands, thyroid, parathyroid, pituitary, nasal cavity, sinuses, ocular carbuncle, lacrimal glands, buccal mucosa, eustachian tube, larynx, esophagus, liver, pancreas, and kidney. [3] The World Health Organization classification of salivary gland neoplasms recognizes three oncocytic entities: oncocytosis, oncocytoma, and oncocytic carcinoma. Oncocytoma is more common than oncocytic carcinomas.…”