“…Bell (1928), Fuss (1935) and Hills and McLanahan (1937) believe this disease is inherited as an autosomal dominant. Seedorff (1949) after studying 55 sibships with 180 affected individuals constructed a scheme based on the theories that each component of the syndrome of osteogenesis imperfecta was the result of a separate gene and that three separate genes controlled the bone fragility, mutation in the three collectively being responsible for osteogenesis imperfecta congenita.…”
“…Bell (1928), Fuss (1935) and Hills and McLanahan (1937) believe this disease is inherited as an autosomal dominant. Seedorff (1949) after studying 55 sibships with 180 affected individuals constructed a scheme based on the theories that each component of the syndrome of osteogenesis imperfecta was the result of a separate gene and that three separate genes controlled the bone fragility, mutation in the three collectively being responsible for osteogenesis imperfecta congenita.…”
“…Sippe II (Ver.) (20,29,32,41,42,51,53,SS). Bei unseren Untersuchungen fanden wir in zwölf Sippen dominant-autosomale Vererbung des Leidens über drei oder mehr Generationen.…”
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