Die Ewingtumoren oder Omoblastome des Knochens

Bethge, Jörn F. J.

doi:10.1007/978-3-642-94642-4_5

Cited by 8 publications

(3 citation statements)

References 196 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Except for Ewing's sarcoma, which occurs more among white people (see Bethge, 1953), race does not appear to be a factor in the incidence of bone tumours.…”

Section: Racementioning

confidence: 99%

See 2 more Smart Citations

Primary Malignant Bone Tumours: A Retrospective Study of 869 Cases Reported to the Finnish Cancer Registry between 1962 and 1968

Jussila

1980

Acta Orthopaedica Scandinavica

View full text Add to dashboard Cite

“…Except for Ewing's sarcoma, which occurs more among white people (see Bethge, 1953), race does not appear to be a factor in the incidence of bone tumours.…”

Section: Racementioning

confidence: 99%

“…Location of primary malignant bone tumours (Coley et al 1950, Wang et a1. 1953, Bethge 1953, Sherman et a1. 1956, Coventry et a1.…”

Section: Locationunclassified

See 1 more Smart Citation

Primary Malignant Bone Tumours: A Retrospective Study of 869 Cases Reported to the Finnish Cancer Registry between 1962 and 1968

Jussila

1980

Acta Orthopaedica Scandinavica

View full text Add to dashboard Cite

Multidisciplinary treatment of primary Ewing's sarcoma of bone.A 6-year experience of a European cooperative trial

Jürgens

Exner

Gadner

et al. 1988

Cancer

408

190

View full text Add to dashboard Cite

The German Society of Pediatric Oncology in 1981 initiated the Cooperative Ewing's Sarcoma Study (CESS 81) using a four-drug combination of chemotherapy prior to definitive local control with surgery and/or radiation. From January 1, 1981 until February 28, 1985, 93 patients were registered at the trial office from 54 participating institutions in West Germany, Austria, Switzerland, and the Netherlands. On February 1, 1987, 54 of 93 patients were disease-free. Using the Kaplan-Meier life table analysis, the estimated disease-free survival (DFS) rate was 60% at 36 months and 55% at 69 months. The median period of observation was 29 months, ranging from 22 months to 69 months. Twenty-one of 93 patients (23%) had local failure, 18 of 93 patients (19%) developed systemic metastases. The local failure rate was particularly high in patients treated with radiation and was reduced when radiation planning was centralized within the study based upon the extent of disease at diagnosis. Cox regression analysis of prognostic factors showed that tumor volume was a significant factor influencing prognosis. The estimated 3-year DFS rate was 80% for patients with small tumors (volume less than 100 ml) compared to 31% for patients with large tumors (volume greater than or equal to 100 ml). In patients who had surgery for local control, the histologic response to chemotherapy was analyzed on the surgical specimen and had a strong influence on survival: 79% DFS at 3 years for patients with less than 10% viable tumor (good responders) compared to 31% DFS for patients with more than 10% viable tumor (poor responders). Tumor load and responsiveness to chemotherapy are the two major factors influencing prognosis in patients with primary Ewing's sarcoma of bone.

show abstract

Diagnosis, Classification, and Nomenclature of Bone Tumors

Schajowicz¹

1977

Bone Tumors

View full text Add to dashboard Cite

Die Ewingtumoren oder Omoblastome des Knochens

Cited by 8 publications

References 196 publications

Primary Malignant Bone Tumours: A Retrospective Study of 869 Cases Reported to the Finnish Cancer Registry between 1962 and 1968

Primary Malignant Bone Tumours: A Retrospective Study of 869 Cases Reported to the Finnish Cancer Registry between 1962 and 1968

Multidisciplinary treatment of primary Ewing's sarcoma of bone.A 6-year experience of a European cooperative trial

Diagnosis, Classification, and Nomenclature of Bone Tumors

Contact Info

Product

Resources

About