Die Hepatitiden B und C bei drogenabhängigen Patienten: Eine epidemiologische Studie*

Background paper to the revised recommendation for hepatitis B vaccination of persons at particular risk and for hepatitis B postexposure prophylaxis in Germany

“…drug users was estimated to be 53% in [2001][2002][2003]. For the same period, HBsAg prevalence was 6.0%-8.4% in this risk group Brack [17] Retrospective cohort study (n=1791) Removille et al [18] Cross-sectional study, Luxembourg…”

“…F Indication group 2: Persons at increased risk of non-occupational exposure.Examples: Persons living together with HBsAg carriers [11,12,13], persons at high risk of acquiring hepatitis B by sexual contact [11,14,15], people who inject drugs [14,16,17], prison inmates [18,19,20], psychiatric inpatients [21,22]. F Indication group 3: Persons at increased risk of occupational exposure.Examples: Health care personnel (HCP) at risk of exposure (including trainees, laboratory personnel, cleaning personnel) [23,24,25], first aiders [26,27], police officers [29], personnel of facilities where an increased prevalence of HBV-infected persons is likely to be present (e.g., correctional facilities, asylum seeker shelters, homes for the handicapped) [18,19,20,27,28,29].…”

Substitutionsbehandlung bei sich prostituierenden heroinabhängigen Frauen - 5-Jahres-Ergebnisse

“…Die Hepatitis-C-Prävalenz ist sehr hoch, auch bei kurzer Suchtdauer: Bereits nach 4 Jahren waren 6 von 7 Frauen infiziert. Das ist sehr viel mehr, als sonst in Hamburg beschrieben [6,7].…”

A large proportion of people who inject drugs are susceptible to hepatitis B: Results from a bio-behavioural study in eight German cities

“…HBV outbreaks among PWID have been repeatedly reported in Europe over the past years (Andersson et al, 2012;Christensen et al, 2001). Studies have identified several risk factors associated with HBV infections among PWID, including age >25 years, sharing needles/syringes, history of needle/syringe sharing in prison, long duration of injecting drug use, homelessness, and unemployment (Andersson et al, 2012;Removille et al, 2011;Stark et al, 1997;Brack, 2002).…”

“…There have been no recent studies providing up-to-date information on HBV among PWID in Germany, and routine monitoring of infections or risk behaviours among PWID has not yet been established. Knowledge on HBV prevalence and vaccination coverage among PWID in Germany is based on outdated regional studies, which found markers of former HBV infection in 35-62% of the study participants and low vaccination coverage (Stark et al, 1997;Brack, 2002;Ridder et al, 2004).…”