Die schwere Pneumonie auf der Intensivstation

Welte, Tobias

doi:10.1007/s00063-016-0165-9

Cited by 10 publications

(1 citation statement)

References 42 publications

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“…[ 3 , 4 ] If it cannot be treated effectively and timely, it can progress to the severe pneumonia (SP). [ 5 – 7 ] SP has higher morbidity and mortality, despite advanced treatment and critical care are applied to those patients. [ 8 – 10 ]…”

Section: Introductionmentioning

confidence: 99%

Ventilator for the management of patients with severe pneumonia

et al. 2020

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Background: This study will assess the efficacy and safety of ventilator for the management of severe pneumonia (SP). Methods: This study will search the following electronic databases in MEDLINE, EMBASE, Web of Science, PsycINFO, Cochrane Library, CNKI, and Scopus from the beginning to present without language restrictions. Two authors will screen all records according to the eligibility criteria; assess study quality; and extract all essential data from eligible studies. If sufficient studies are included, we will pool the extracted data and carry out meta-analysis. Results: This study will summarize published studies to assess the efficacy and safety of ventilator for patients with SP. Conclusion: The results of this study may supply a genuine understanding of perspective from a scientific basis on ventilator for the management of patients with SP.

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Section: Introductionmentioning

confidence: 99%

Ventilator for the management of patients with severe pneumonia

et al. 2020

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Boliden auf der Intensivstation

Kielstein

Kruse

Anderson

et al. 2017

Med Klin Intensivmed Notfmed

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We would neither be disappointed nor upset if the gas mileage on the sticker of a car didn't match our personal, real-life fuel consumption. Depending on our daily route to work, our style of accelerating and the number of passengers in our carpool, the gas mileage will vary. As soon as the falcon wing door of our car is closed and entrance to the ICU is granted, we tend to forget all of this, even though another hot rod is waiting there for us. Renal replacement therapy is like a car; it fulfills goals, such as the removal of uremic toxins and accumulated fluids, but it also "consumes" (removes) antibiotics. Unlike catecholamines, where we have the mean arterial pressure on our ICU dashboard, we do not have a gauge to measure antibiotic "consumption", i.e. elimination by renal replacement therapy. This manuscript describes the principles and basic knowledge to improve dosing of antibiotics in critically ill patients undergoing renal replacement therapy. As in modern cars, we briefly touch on hybrid therapies combining renal replacement therapy with extracorporeal lung support or adsorbent technologies that remove cytokines or bacteria. Further, the importance of considering body size and body composition is addressed, especially for choosing the right initial dose of antibiotics. Lastly we point out the dire need to increase the availability of timely and affordable therapeutic drug monitoring on the most commonly used antiinfectives, ideally using point-of-care devices at the bedside.

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