“…Thus, maintaining the integrity and functions of intestinal barrier is essential for human and animal health [13] . The weaning stress of piglets can cause immune system destruction, intestinal microbiome dysbiosis, and intestinal barrier dysfunction, then leading to intestinal injury and poor health, thus reducing the growth performance, diarrhea occurrence, and even death [2,3,[33][34][35][36] . LPS is a component of the outer cell wall of Gram-negative bacteria.…”