Dietary Intakes of Patients with Alcohol Use Disorder During a 4-Week Protocol on an Inpatient Treatment Unit Found to Meet Dietary Reference Intakes for Macronutrients, but Have Variability in Energy Balance and Adequacy of Micronutrient Intake

Yang, Shanna; Ratteree, Kelly; Turner, Sara A.; Tuason, Ralph Thadeus; Brooks, Alyssa T; Wallen, Gwenyth R.; Barb, Jennifer

doi:10.1016/j.jand.2022.05.022

Cited by 2 publications

(2 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[115][116][117] Patients with AUD are at risk of vitamin and mineral deficiencies, malnutrition, obesity, neurologic disease, and metabolic syndrome. [118,119] Engagement in exercise may reduce alcohol cravings, enhance mood, improve sleep, and coping. [116,117] Opportunity: Centers of Excellence for post-LT AUD care…”

Section: Pennmentioning

confidence: 99%

“…Evidence supporting interventions related to nutrition and exercise is emerging 115–117 . Patients with AUD are at risk of vitamin and mineral deficiencies, malnutrition, obesity, neurologic disease, and metabolic syndrome 118,119 . Engagement in exercise may reduce alcohol cravings, enhance mood, improve sleep, and coping 116,117 …”

Section: Challenge #4: Post-lt Relapse Poses Demands On the Transplan...mentioning

confidence: 99%

See 1 more Smart Citation

Management of alcohol-associated liver disease and alcohol use disorder in liver transplant candidates and recipients: Challenges and opportunities

Sharma,

Shenoy,

Shroff

et al. 2024

Liver Transplantation

View full text Add to dashboard Cite

Alcohol-associated liver disease (ALD) poses a significant global health burden, with rising alcohol consumption and prevalence of alcohol use disorder (AUD) contributing to increased morbidity and mortality. This review examines the challenges and opportunities in the care of liver transplant (LT) candidates and recipients with AUD. Despite advancements in post-transplant patient survival, the risk of disease recurrence and alcohol relapse remains substantial. Several challenges have been identified, including (1) rising disease burden of ALD, variable transplant practices, and systemic barriers; (2) disparities in mental health therapy access and the impact on transplant; (3) variable definitions, underdiagnosis, and stigma affecting access to care; and (4) post-LT relapse, its risk factors, and consequential harm. The review focusses on the opportunities to improve AUD care for LT candidates and recipients through effective biochemical monitoring, behavioral and pharmacologic approaches, creating Centers of Excellence for post-LT AUD care, advocating for policy reforms, and ensuring insurance coverage for necessary services as essential steps toward improving patient outcomes. The review also highlights unmet needs, such as the scarcity of addiction specialists, and calls for further research on personalized behavioral treatments, digital health, and value-based care models to optimize AUD care in the LT setting.

show abstract

Section: Pennmentioning

confidence: 99%

Section: Challenge #4: Post-lt Relapse Poses Demands On the Transplan...mentioning

confidence: 99%

Management of alcohol-associated liver disease and alcohol use disorder in liver transplant candidates and recipients: Challenges and opportunities

Sharma,

Shenoy,

Shroff

et al. 2024

Liver Transplantation

View full text Add to dashboard Cite

show abstract

Multi‐domain predictors of grip strength differentiate individuals with and without alcohol use disorder

Paschali,

Zhao,

Sassoon

et al. 2024

Addiction Biology

View full text Add to dashboard Cite

Grip strength is considered one of the simplest and reliable indices of general health. Although motor ability and strength are commonly affected in people with alcohol use disorder (AUD), factors predictive of grip strength decline in AUD have not been investigated. Here, we employed a data‐driven analysis predicting grip strength from measurements in 53 controls and 110 AUD participants, 53 of whom were comorbid with HIV infection. Controls and AUD were matched on sex, age, and body mass index. Measurements included commonly available metrics of brain structure, neuropsychological functioning, behavioural status, haematological and health status, and demographics. Based on 5‐fold stratified cross‐validation, a machine learning approach predicted grip strength separately for each cohort. The strongest (top 10%) predictors of grip were then tested against grip strength with correlational analysis. Leading grip strength predictors for both cohorts were cerebellar volume and mean corpuscular haemoglobin concentration. Predictors specific to controls were Backwards Digit Span, precentral gyrus volume, diastolic blood pressure, and mean platelet volume, which together significantly predicted grip strength (R2 = 0.255, p = 0.001). Unique predictors for AUD were comorbidity for HIV infection, social functioning, insular volume, and platelet count, which together significantly predicted grip strength (R2 = 0.162, p = 0.002). These cohort‐specific predictors were doubly dissociated. Salient predictors of grip strength differed by diagnosis with only modest overlap. The constellation of cohort‐specific predictive measurements of compromised grip strength provides insight into brain, behavioural, and physiological factors that may signal subtly affected yet treatable processes of physical decline and frailty.

show abstract

Dietary Intakes of Patients with Alcohol Use Disorder During a 4-Week Protocol on an Inpatient Treatment Unit Found to Meet Dietary Reference Intakes for Macronutrients, but Have Variability in Energy Balance and Adequacy of Micronutrient Intake

Cited by 2 publications

References 24 publications

Management of alcohol-associated liver disease and alcohol use disorder in liver transplant candidates and recipients: Challenges and opportunities

Management of alcohol-associated liver disease and alcohol use disorder in liver transplant candidates and recipients: Challenges and opportunities

Multi‐domain predictors of grip strength differentiate individuals with and without alcohol use disorder

Contact Info

Product

Resources

About