Dietary selenium fortification: a potential solution to chronic arsenic toxicity

Sah, Shweta; Smits, Judit E. G.

doi:10.1080/02772248.2012.701104

Cited by 13 publications

(6 citation statements)

References 38 publications

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“…In recent years, in vitro research showed that Se can alleviate arsenic toxicity by modifying cytotoxicity, genotoxicity and oxidative stress [46,47]. This is confirmed by a study carried out by Sah and Smits (2012), who suggested dietary Se at 0.6 mg/ kg, improved the antioxidant capacity and counteracted chronic as toxicity in rats [48]. It was also demonstrated that Se at 0.3 mg/kg in diets can improve immunity to counter As-induced immunotoxicity [49].…”

Section: Discussionmentioning

confidence: 80%

Evaluation of Essential and Toxic Elements in Blood Samples of Male Smokers Having Different Types of Cancers with Reference to Healthy Male Smokers

Kazi¹

2016

J. Clinical Medi. Res. Updates

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Immense epidemiologic studies have been reported about the role of essential trace and toxic elements as risk factors for incidence of different type of cancers in population of developed and developing countries. In present work the levels of carcinogenic, Arsenic, Cadmium, and Nickel (As, Cd and Ni) and anti-carcinogenic, Zinc and Selenium (Zn and Se) elements were measured in blood of male cancer patients (urinary bladder, lung, mouth and esophageal) and healthy referents. The all patients and referents were smoker. The blood samples were analysed with atomic absorption spectrometry after microwave assisted acid digestion. The resulted data indicated that the levels of toxic elements As, Ni and Cd were considerably elevated whereas essential elements, Zn and Se were lower in blood samples of all cancer cases as compared to those values found in noncancerous subjects. As the levels of essential trace elements were low in blood samples of male cancerous patients but difference was highly significant in lung and mouth cancer subjects (p<0.001), whereas sequence of decreasing order was not uniform. The levels of Zn in blood samples of different cancerous patients were found in decreasing order as: esophagus< mouth< urinary bladder

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Section: Discussionmentioning

confidence: 80%

Evaluation of Essential and Toxic Elements in Blood Samples of Male Smokers Having Different Types of Cancers with Reference to Healthy Male Smokers

Kazi¹

2016

J. Clinical Medi. Res. Updates

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“…In a recent animal study, male Wistar rats were given drinking water containing As. The rats were divided into Se-deficient, Se-adequate, and Se-fortified diet groups, and the Se-fortified diet was found to help with As excretion (Sah and Smits, 2012). As and Se distribute similarly throughout the body due to their similar chemical properties (Gailer, 2007).…”

Section: Introductionmentioning

confidence: 99%

Soft tissue measurement of arsenic and selenium in an animal model using portable X-ray fluorescence

Fleming

Groves

Gherase

et al. 2015

Radiation Physics and Chemistry

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“…The moderate positive correlation between As and Se in this study corroborates previous evidence (Lucia et al 2012 ) and can be explained by their interaction (Sun et al 2014 ). Selenium in small amounts has been shown to ameliorate As toxicity in different ways (Sah and Smits 2012 ).…”

Section: Resultsmentioning

confidence: 99%

Lead, cadmium, and other trace elements in the liver of golden eagles and white-tailed eagles: recent data from Poland and a systematic review of previous studies

Durkalec

Nawrocka

Kitowski

et al. 2022

Environ Sci Pollut Res

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The golden eagle (Aquila chrysaetos) and the white-tailed eagle (Haliaeetus albicilla), being apex predators and facultative scavengers, can bioaccumulate different environmental contaminants, including toxic elements that may adversely affect their health. We analyzed the levels of cadmium (Cd), lead (Pb), and other metals and metalloids, including arsenic (As), barium (Ba), beryllium (Be), cobalt (Co), chromium (Cr), copper (Cu), iron (Fe), magnesium (Mg), manganese (Mn), molybdenum (Mo), selenium (Se), thorium (Th), thallium (Tl), uranium (U), vanadium (V), and zinc (Zn) in liver samples taken from three golden eagles and 36 white-tailed eagles that were found dead across Poland to verify their exposure. We also used a systematic review to summarize the available literature data on Cd, Pb, and other studied elements in the liver of both eagle species. Analyses of trace elements in the liver samples of the Polish eagles revealed interspecific differences in Cd, Cu, and Mn and differences in Co, Mn, Tl, and Zn among study regions. All elements tested except Pb were below the suggested thresholds linked with adverse health effects in birds. The hepatic Pb found in almost half of all the tested individuals suggests environmental exposure to this toxic element. One of the tested white-tailed eagles had hepatic Pb above the threshold of sublethal poisoning. Although our results seem optimistic, as previous Polish studies showed a higher prevalence of birds with hepatic Pb exceeding the toxicity threshold, they indicate that exposure to this toxic metal could still pose an additional threat to the health of Polish eagles. Graphical abstract

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Dietary selenium fortification: a potential solution to chronic arsenic toxicity

Cited by 13 publications

References 38 publications

Evaluation of Essential and Toxic Elements in Blood Samples of Male Smokers Having Different Types of Cancers with Reference to Healthy Male Smokers

Evaluation of Essential and Toxic Elements in Blood Samples of Male Smokers Having Different Types of Cancers with Reference to Healthy Male Smokers

Soft tissue measurement of arsenic and selenium in an animal model using portable X-ray fluorescence

Lead, cadmium, and other trace elements in the liver of golden eagles and white-tailed eagles: recent data from Poland and a systematic review of previous studies

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