Dietary supplementation with tomato-juice in patients with metabolic syndrome: A suggestion to alleviate detrimental clinical factors

Tsitsimpikou, Christina; Tsarouhas, Konstantinos; Kioukia‐Fougia, Nassia; Skondra, Christina; Fragkiadaki, Persefoni; Papalexis, Petros; Stamatopoulos, Panagiotis; Kaplanis, Ioannis; Hayes, A. Wallace; Tsatsakis, Aristidis; Rentoukas, Elias

doi:10.1016/j.fct.2014.08.014

Cited by 42 publications

(34 citation statements)

References 40 publications

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“…HDL-C plays an important role in carrying cholesterol from peripheral tissues and cells to organs, while LDL-C and VLDL-C can carry cholesterol in the serum to peripheral tissues [ 29 ]. This ability was agreed well with the other natural plant product of tomato juice, which had activities of lowing the LDL values and positively attenuating both the glycemia and dyslipidemia against metabolic syndrome in patient [ 30 ]. Furthermore, TC and TG are two essential parameters for assessing blood viscosity and the risk of atherosclerosis.…”

Section: Discussionsupporting

confidence: 70%

Characterization and Attenuation of Streptozotocin‐Induced Diabetic Organ Damage by Polysaccharides from Spent Mushroom Substrate (Pleurotus eryngii)

Liu

Yao

Zhao

et al. 2018

Oxidative Medicine and Cellular Longevity

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The aim of this work was to characterize spent mushroom substrate polysaccharides (MSP) from Pleurotus eryngii and their antioxidant and organ protective effects in streptozotocin- (STZ-) induced diabetic mice. The enzymatic-, acidic-, and alkalic- (En-, Ac-, and Al-) MSP were extracted from P. eryngii with snailase (4%), hydrochloric acid (1 mol/l), and sodium hydroxide (1 mol/l), respectively. The characterizations were evaluated by spectral analysis. In animal experiments, the enzymatic activities, lipid peroxide contents, and serum lipid parameters were measured, and histological observations of the liver, kidney, pancreas, and heart were conducted. The results demonstrated that treatment with En-, Ac-, and Al-MSP increased the organ enzymatic activities, decreased the organ lipid peroxide contents, mitigated the serum biochemistry values, and ameliorated the histopathology of diabetic mice, indicating that En-, Ac-, and Al-MSP could potentially be used as functional foods for the prevention of diabetes.

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Section: Discussionsupporting

confidence: 70%

Characterization and Attenuation of Streptozotocin‐Induced Diabetic Organ Damage by Polysaccharides from Spent Mushroom Substrate (Pleurotus eryngii)

Liu

Yao

Zhao

et al. 2018

Oxidative Medicine and Cellular Longevity

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“…The main biological mechanism by which lycopene reduces the risk and mortality of the metabolic syndrome , include the antioxidant, anti-inflammatory and antiobesity effects, the ability to improve endothelial function, glycemic control, insulin sensitivity and lipid profile (Tsitsimpikou et al, 2014 ; Li et al, 2015 ; Han et al, 2016a , b ). An inverse relationship was found by Yeo et al between lycopene level and brachial-ankle pulse wave velocity (Yeo et al, 2011 ).…”

Section: Clinical Researchmentioning

confidence: 99%

Lycopene and Vascular Health

et al. 2018

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Lycopene is a lipophilic, unsaturated carotenoid, found in red-colored fruits and vegetables, including tomatoes, watermelon, papaya, red grapefruits, and guava. The present work provides an up to date overview of mechanisms linking lycopene in the human diet and vascular changes, considering epidemiological data, clinical studies, and experimental data. Lycopene may improve vascular function and contributes to the primary and secondary prevention of cardiovascular disorders. The main activity profile of lycopene includes antiatherosclerotic, antioxidant, anti-inflammatory, antihypertensive, antiplatelet, anti-apoptotic, and protective endothelial effects, the ability to improve the metabolic profile, and reduce arterial stiffness. In this context, lycopene has been shown in numerous studies to exert a favorable effect in patients with subclinical atherosclerosis, metabolic syndrome, hypertension, peripheral vascular disease, stroke and several other cardiovascular disorders, although the obtained results are sometimes inconsistent, which warrants further studies focusing on its bioactivity.

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“…Other studies using tomato juice [77] or tomato-based drinks [78] have shown beneficial effects on inflammation. In another study with tomato juice, individuals with metabolic syndrome had a significant improvement in inflammation status and endothelial dysfunction after having tomato juice four times a week over a period of two months compared with the control group [79]. Specifically, tomato products consumed with a high-fat meal were effective at attenuating postprandial lipemiainduced oxidative stress and associated inflammatory response (notably, the rise in IL-6) in healthy individuals [80].…”

Section: Red Foods and Inflammationmentioning

confidence: 97%

A Review of the Science of Colorful, Plant-Based Food and Practical Strategies for “Eating the Rainbow”

Minich

2019

Journal of Nutrition and Metabolism

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Over the past decades, thousands of published studies have amassed supporting recommendations to consume fruits and vegetables for physiological and psychological health. Newer research has emerged to suggest that these plant-based foods contain a plethora of not only vitamins and minerals, but perhaps, most importantly, phytonutrients. These phytonutrients have known pleiotropic effects on cellular structure and function, ultimately resulting in the modulation of protein kinases and subsequent epigenetic modification in a manner that leads to improved outcomes. Even though eating fruits and vegetables is a well-known feature of a healthy dietary pattern, population intakes continue to be below federal recommendations. To encourage consumers to include fruits and vegetables into their diet, an “eat by color” approach is proposed in this review. Although each individual food may have numerous effects based on its constituents, the goal of this simplified approach was to identify general patterns of benefits based on the preponderance of scientific data and known mechanisms of food-based constituents. It is suggested that such a consumer-oriented categorization of these plant-based foods may lead to greater recognition of their importance in the daily diet throughout the lifespan. Other adjunctive strategies to heighten awareness of fruits and vegetables are discussed.

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Dietary supplementation with tomato-juice in patients with metabolic syndrome: A suggestion to alleviate detrimental clinical factors

Cited by 42 publications

References 40 publications

Characterization and Attenuation of Streptozotocin‐Induced Diabetic Organ Damage by Polysaccharides from Spent Mushroom Substrate (Pleurotus eryngii)

Characterization and Attenuation of Streptozotocin‐Induced Diabetic Organ Damage by Polysaccharides from Spent Mushroom Substrate (Pleurotus eryngii)

Lycopene and Vascular Health

A Review of the Science of Colorful, Plant-Based Food and Practical Strategies for “Eating the Rainbow”

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