Difference Between Cryotherapy and Follow Up Low Grade Squamous Lesion of Cervix Uteri

Jahic, Mahira; Jahić, Elmir; Mulavdic, Mirsada; Hadzimehmedovic, Azra

doi:10.5455/medarh.2017.71.280-283

Cited by 9 publications

(7 citation statements)

References 20 publications

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“…Abnormal colposcopic findings in HSIL lesions were found in 72.9% (N-69) and in ASC-H lesions in 40.5% (N-15). Colposcopic examination has better results in differentiating high-grade lesions from lower-grade lesions and correlates with direct biopsy and is described as the gold standard in the diagnosis of precancerous lesions ( 12 , 13 , 14 ), as shown by our study. Colposcopy showed better sensitivity in this study in 72,9% (N-69) compared to cytology which showed 67.7% (N-55).…”

Section: Discussionsupporting

confidence: 65%

Cytological, Colposcopic and Pathohistological Correlation of HSIL and ASC H Findings

Jahic

Hadzimehmedovic

2020

Med Arch

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Section: Discussionsupporting

confidence: 65%

Cytological, Colposcopic and Pathohistological Correlation of HSIL and ASC H Findings

Jahic

Hadzimehmedovic

2020

Med Arch

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“…Four weeks after the treatment, epithelisation of cervix was found in 87,40%, and after 6 weeks in 93,50%. In similar research of efficiency of cryotherapy, Jahic finds efficiency in 89,3%, Peck in 91%, Alvarez in 92%, Gay in 95% while the Alliance for prevention of cervical cancer confirmed that the efficiency of cryotherapy in women with cervical intraepithelial lesion is 98,5% (6).…”

Section: Discussionmentioning

confidence: 91%

Cryotherapy of Erosion of Cervix and Low Grade Squamous Intraepithelial Lesion

Jahic¹

2018

Mater Sociomed

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Introduction: Cervical erosion and squamouse intraepithelial lesion of low grade are most common gynecological problems of women. These changes on cervix are cause of painful coitus and enhanced vaginal secretion. Cryotherapy is widely accepted method in treating these changes and sympthoms. Aim: The aim of this study is to examine the efficiency of cryotherapy in eliminating erosion of cervics and LSIL, as well as conditions following these states. Patients and methods: Cryotherapy was performed in 124 women with cervical erosion (N-74) and LSIL (N-50). Sympthoms that were followed are: vaginal secretion, abnormal vaginal bleeding and pain. Assessment of epithelisation of cervix and evaluation of sympthoms were done 4 and 6 weeks after cryotherapy and PAP test after 4 months in women with LSIL. Statistical method used in result processing was X2 test. Results: The average age of examined women is 37,75±8,2. Enhanced vaginal secretion had 87,09% (N-120), painful coitus 61,29% (N-76), pain in lesser pelvis 52,41% (N-65) and abnormal vaginal bleeding 28,22% (N-35). Erosion of cervix had 14% (N-7) of women with LSIL. After cryotherapy, enhanced vaginal secretion remained in 21,77% (N-27) of women, painful coitus remained in 8,06% (N-10), pain in lesser pelvis remained in 5,6% (N-7) and abnormal vaginal bleeding in 6,4% (N-8). Four weeks after cryotherapy, complete epithelisation of cervix was in 87,90% (N-109) and after six weeks in 93,54% (N-116) of examined women. LSIL was eliminated in 92% (N-46) of women after cryotherapy and in 8% (N-4) results remained the same. Conclusion: Cryotherapy is successful method of elimination of cervical erosion, LSIL and pains with enhanced vaginal secretion.

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“…The percentage of representation of HPV is significantly more frequent in HSIL (90% to 100%). Untreated LSIL can progress in 13% of cases to HSIL during 2 years of monitoring ( 9 , 10 ). Women infected with HPV 16 have a transition of LSIL into HSIL in 9% of cases.…”

Section: Discussionmentioning

confidence: 99%

Progression Low Squamous Intraepithelial Lesion and Human Papillomavirus Infections

Jahic¹,

Kamerić²,

Hadzimehmedovic³

2020

Mater Sociomed

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Introduction: Infection with human papillomavirus is the main cause of cervical carcinoma. In Bosnia and Herzegovina (BIH) 556 cases of cervical carcinoma are diagnosed annually, and 141 women die from it. Aim: To determine the most common HPV type found in ASCUS and LSIL and progression, regression and persistence of lesions. Methods: In a retrospective study, 11 051 PAP tests, performed in several private gynecological practices located in Tuzla Canton from January 2016 to December 2019, were analyzed. In processing of data , X 2 – statistical method was used. Results: 11051 PAP test were inspected. Normal findings were found in 90.48% (N-10002) and pathological findings in 9.49% (N- 049). ASCUS was present in 4.9% (N-544), LSIL in 3.04% (N-337), HSIL in 0.74% (N-84), ASC-H in 0.27% (N-30) and AGC in 0.49% (N-55) of cases. The most common is HPV 16, found in 50.5% (N-44) of ASCUS and LSIL. Monoinfection with HPV 16 was found in 40.9% (N-18) ASCUS (N-3) and LSIL (N-15), and a combination of HPV 16 with other types like HPV 18, 31, 33, 39 in 59% (N-26). Progression of ASCUS lesion in HSIL 1.6% (N-2), and LSIL 9.6% (N-12). Progression of LSIL to HSIL was found in 9.0% (N-10). HSIL progresses significantly more frequent from LSIL (p<0.05) than from ASCUS changes. Lesions that progress into higher grade HSIL are HPV 16 positive. Progression into HSIL is not found in patients with low-risk HPV 6 and 11 infection. Conclusion: Women infected with HPV 16 have more a frequent progression of a lesion into higher grade HSIL. They should be intensively monitored because of the increased risk for development of cervical carcinoma.

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Difference Between Cryotherapy and Follow Up Low Grade Squamous Lesion of Cervix Uteri

Cited by 9 publications

References 20 publications

Cytological, Colposcopic and Pathohistological Correlation of HSIL and ASC H Findings

Cytological, Colposcopic and Pathohistological Correlation of HSIL and ASC H Findings

Cryotherapy of Erosion of Cervix and Low Grade Squamous Intraepithelial Lesion

Progression Low Squamous Intraepithelial Lesion and Human Papillomavirus Infections

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