Difference in Blood Pressure Values From Observed and No Observed Blood Pressure Measurements With Awake Blood Pressure

Abstract

Objective: Evaluate the correlation and agreement of blood pressure (BP) values from observed and non-observed measurements with awake blood pressure (ABP). Translate the results of the difference between observed and awake BP into SPRINTb Ambulatory Blood Pressure Study. Design and method: Two hundred seventy-eight patients over eighteen years old were eligible. After 5 minutes on rest, a nurse collected clinical characteristics, took three sequential observed (OBP) and non-observed (N-OBP) BP measurements (Microlife- BP 3AC1–1PC), in an alternate order, every fifteen seconds. Also, was recorded twenty-four hours of ABPM (DynaMAPA). BP measurements and ABPM recording followed recommendations of European Guidelines. We calculated Cardiovascular (CV) risk using the SCORE system. aa well as, the average of OBP, N-OBP, awake BP (ABP), and the difference OBP-ABP. We assessed the relationship of observed or non-observed BP values with ABP by calculating the Pearson coefficient (r), and the agreement using a Bland–Altman plot. The significance of differences between average BP values was evaluated using analysis of covariance and Student's T-Test into variance in OBP-ABP. Results: Among 278 patients, 48.6% performed non-observed BP measurements firstly. Demographic and main clinical characteristics were demonstrated in table 1, as well as, all BP media and the differences between OBP-ABP in four subgroups of the studied population. The table below shows p values p values to compared of BP average and differences on BP. Figure 1 shows a Bland Altman plot of the agreement between tested BP against ABP. Figure 2 shows the results of the correlation between the tested BP and ABP. The red marks on X-axis are the ABP values on standard (S - 138.8/78.6) and intensive (I - 126.5/72.0) groups at the end of 27 months of the ABP SPRINT Study, and those on Y-axis the corresponding values of OBP and N-OBP, according to the differences with ABP found in this study. Conclusions: In conclusion, the findings of this study showed a strong correlation and a significant difference to both observed, no observed BP values with awake BP. Our results could be useful in interpreting the ABP SPRINT Study.