Differences Between Breast Cancer Patients Younger and Older than 40 Years: Mammographic Findings

Yu, Zhongjian; Wang, Jian Tao; Liu, Jing; Ju, Wang; Wang, Hong Li; Liu, Pei Fang

doi:10.7314/apjcp.2014.15.12.4929

Cited by 5 publications

(6 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is similar to a previous study conducted by Zhao et al in which circumscribed and microlobulated masses on mammography were more common among younger cases, and estimated at 13.9% in the younger group. 35 Regarding margin, there is an additional point that the most common mass margin was indistinct which is consistent with some previous studies. 35 In our research, all the neoplastic masses were hypoechoic which is compatible with previous studies.…”

Section: Discussionsupporting

confidence: 90%

Assessment of Ultrasound Features and BI-RADS Categories of Malignant Breast Masses in Women ≤40

et al. 2021

View full text Add to dashboard Cite

Background: To evaluate ultrasound (US) characteristics and BI-RADS (Breast imaging-reporting and data system) of malignant breast masses in women <40 years and to compare with older patients. Methods: In a retrospective, descriptive-analytical study, we assessed the US images and BI-RADS category of 78 malignant masses with a final pathology of invasive ductal carcinoma (IDC, NOS type). Results: Overall, the most frequent US descriptors of IDC were indistinct margin (45%), irregular shaped (63.5%), posterior shadowing (38.8%), heterogeneous internal echogenicity (56.3%) and non-parallel orientation (76.3%). In this study, most malignant masses of young patients were categorized as BI-RADS 4a while in the older patients (over 40), they were mostly BI-RADS 4b and 5 with P = 0.03 and odds ratio (OR) of 2.57 (95% confidence interval (CI), 0.74-8.8). In addition, the mean dimension of the mass in young cases was greater (18.3 mm) compared with older patients (13.2 mm) with P value of 0.04 and OR of 3.8 (95% CI, 1.1-13.4). Conclusion:Similar to previous studies, malignant masses were diagnosed in greater dimensions in younger cases which may be due to the delay in diagnosis, the rapid growth of the tumor and the absence of routine screening guidelines. Radiologists should be aware of the possibility of malignancy in palpable slightly suspicious masses (BI-RADS 4A) in young cases.

show abstract

Section: Discussionsupporting

confidence: 90%

Assessment of Ultrasound Features and BI-RADS Categories of Malignant Breast Masses in Women ≤40

et al. 2021

View full text Add to dashboard Cite

show abstract

“…On breast cancer screening for young women, we should be aware of the features of mammograms in young patients with breast cancer to maintain high sensitivity. Zhao et al, (2014) showed that the number of young patients with a mammographic focus who had microcalcifications was significantly more than that of old patients (44.2% vs. 39.4%, P = 0.001). Additionally, considering the high prevalence of dense breasts among young women, microcalcifications are important findings in young patients with breast cancer.…”

Section: Discussionmentioning

confidence: 95%

“…Because of the high frequency of high-density breasts in young women, studies have assessed the characteristic findings in young women, particularly those with a mass and focal asymmetric density (Osako et al, 2007;Zhao et al, 2014). Few studies have examined the characteristics of breast microcalcifications on screening mammography in young women.…”

Section: Features Of Microcalcifications On Screening Mammography In mentioning

confidence: 99%

Features of Microcalcifications on Screening Mammography in Young Women

Fushimi¹,

Fukushima

Suzuki

et al. 2018

Asian Pac J Cancer Prev

View full text Add to dashboard Cite

Background: There is no decrease in the number of breast cancer deaths if screening mammography is performed in women aged <40 years. However, NCCN guidelines recommend screening mammography in young women at risk of hereditary breast cancer. Therefore, more accurate screening mammography for young women is needed. Objective: To evaluate the features of screening mammographic findings, particularly microcalcifications, in women aged <50 years to increase the positive predictive value of screening mammography in young women. Methods: We retrospectively reviewed the data of consecutive women who underwent opportunistic and organized breast cancer screening at the Sakuragaoka Hospital (Shizuoka, Japan) between April 2013 and March 2015. We compared the mammographic findings and features of microcalcifications between women aged <40 and 40–49 years and those aged 50–74 years. Results: The study included 3645 women. Of these 3645 women, 415 (11.4%) were aged <40 years, 1219 (33.4%) were aged 40–49 years, and 2011 (55.2%) were aged 50–74 years. Women aged <50 years were more likely to be recalled for microcalcifications than those aged 50–74 years (<40 years, 4.8%; 40–49 years, 4.3%; 50–74 years, 3.3%). Young women were more likely to be recalled for small round and segmental microcalcifications [<40 years, odds ratio (OR): 1.799 (95% CI: 0.751–2.846); 40–49 years, OR: 1.394 (95% CI: 0.714–2.074)] and less likely to be recalled for small round and grouped microcalcifications [<40 years, OR: 0.603 (95% CI: 0.181–1.025); 40–49 years, OR: 0.961 (95% CI: 0.496–1.428)] compared with women aged 50–74 years. Conclusions: On screening mammography, women aged <50 years had a higher tendency to be recalled for microcalcifications, particularly small round and segmental microcalcifications. False-positive results may be reduced by reflecting the characteristics of microcalcification findings among young women without breast cancer in the future.

show abstract

“…Mammographic density and the age-specific incidence of breast cancer differ markedly between women in Asian and Western countries [ 10 - 13 ]. Therefore, there may be differences in the relationship between breast density and breast cancer risk in Asian women [ 9 ], including Korean women [ 14 , 15 ], compared to women in Western countries.…”

Section: Introductionmentioning

confidence: 99%

Distribution of Dense Breasts using Screening Mammography in Korean Women: a Retrospecitive Observational Study

Bae

Shin²,

Kim

et al. 2014

Epidemiol Health

View full text Add to dashboard Cite

OBJECTIVES:This retrospective observational study evaluated the distribution of dense breasts by age group among healthy Korean women.METHODS:Participants were women aged 30 years and older who voluntarily underwent screening mammography between January 2007 and December 2011. Women who received the Breast Imaging Reporting and Data System for mammographic density of 3 or 4 were defined as having dense breasts. The proportion of women with dense breasts (PDB, %) was calculated by dividing the number of participants with dense breasts by the total number of participants.RESULTS:Among the 231,058 women who participated, 78.15% were classified as having dense breasts. PDB was highest in the youngest age group (PDB=94.87%) and lowest in the oldest age group. The greatest difference in PDB between adjacent age groups was observed in the group aged 60-64 years.CONCLUSIONS:The results show that the proportion of dense breasts by age group increased in all age groups, except in those aged 35-39 years. These findings suggest an association between the age distribution of dense breasts and trends in breast cancer incidence. Further studies are needed to estimate the change in breast cancer incidence rate by age and the accumulation of fatty breast tissue in Korean women.

show abstract

Differences Between Breast Cancer Patients Younger and Older than 40 Years: Mammographic Findings

Cited by 5 publications

References 21 publications

Assessment of Ultrasound Features and BI-RADS Categories of Malignant Breast Masses in Women ≤40

Assessment of Ultrasound Features and BI-RADS Categories of Malignant Breast Masses in Women ≤40

Features of Microcalcifications on Screening Mammography in Young Women

Distribution of Dense Breasts using Screening Mammography in Korean Women: a Retrospecitive Observational Study

Contact Info

Product

Resources

About