Differences in Heart Failure-Related Cardiogenic Shock Between Ischemic and Nonischemic Cardiomyopathy: Data From the Critical Care Cardiology Trials Network

Feinman, Jason; Tomey, Matthew Ian; Serrao, Gregory; Moss, Noah; Ronquillo, María; Martillo, Miguel; Palazzolo, Michael G.; Diepen, Sean van; Katz, Jason N.; Bohula, Erin A.; Berg, David Van Den; Morrow, David A.; Gidwani, Umesh; Leibner, Evan

doi:10.1016/s0735-1097(23)00891-4

Cited by 1 publication

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the CCCTN registry, ICM-CS excluding AMI-CS was associated with older age, higher rates of comorbidities, and poorer prognosis compared with non-ICM-CS. 28 Data from European Society of Cardiology HF registries showed similar results in patients with HF with reduced ejection fraction. 29 However, in the current study, after strict adjustment for comorbidities and baseline differences, non-ICM-CS was associated with a slightly higher risk of mortality and the use of cardiac replacement therapy than ICM-CS.…”

Section: Discussionmentioning

confidence: 88%

“…However, AMI‐CS and ICM‐CS have different pathophysiology, treatment strategies, and prognosis; therefore, they should be analysed separately. In the CCCTN registry, ICM‐CS excluding AMI‐CS was associated with older age, higher rates of comorbidities, and poorer prognosis compared with non‐ICM‐CS 28 . Data from European Society of Cardiology HF registries showed similar results in patients with HF with reduced ejection fraction 29 .…”

Section: Discussionmentioning

confidence: 94%

See 1 more Smart Citation

In‐hospital and long‐term outcomes of cardiogenic shock complicating myocardial infarction versus heart failure

Choi,

Kang,

Park

et al. 2024

European J of Heart Fail

View full text Add to dashboard Cite

AimsThis study sought to examine the difference in clinical characteristics, treatment strategy, trends in mortality, and medical costs according to the aetiologies of cardiogenic shock (CS).Methods and resultsThis was a population‐based, nationwide, cohort study from the Korean National Health Insurance Service database. All CS adults (≥18 years) were admitted to an intensive care unit from January 2010 to December 2020. The primary outcome was in‐hospital mortality. The secondary outcomes were cardiac replacement therapy (left ventricular assisted device implantation or heart transplantation), all‐cause mortality, ischaemic stroke, rehospitalization for heart failure (HF) during follow‐up, and actual in‐hospital medical costs. Among 136 092 individuals with CS, 48 704 (29.7%) cases were due to acute myocardial infarction‐related CS (AMI‐CS), and the remaining 87 388 (71.3%) were due to HF‐CS (ischaemic cardiomyopathy [ICM] vs. non‐ICM, 49 504 [56.6%] vs. 37 884 [45.4%]). Patients with HF‐CS were older, less likely to be male, and less likely to receive mechanical circulatory support, compared to those with AMI‐CS. During the 10‐year study period, the in‐hospital mortality rate decreased, and actual medical costs tended to increase, regardless of CS aetiology. Compared with AMI‐CS, HF‐CS was associated with higher risks of in‐hospital mortality (40.3% vs. 28.5%; adjusted odds ratio [OR] 1.47, 95% confidence interval [CI] 1.43–1.52), cardiac replacement therapy (adjusted OR 1.65, 95% CI 1.16–2.34), as well as follow‐up mortality after successful discharge (19.3% vs. 8.5%; adjusted‐hazard ratio 1.54, 95% CI 1.48–1.59). HF‐CS had lower medical costs than AMI‐CS (adjusted ratio 0.79, 95% CI 0.79–0.80).ConclusionsWith medical advances during the past 10 years, the mortality of CS has decreased significantly, but the mortality of HF‐CS remains high. The findings highlight the need for effective treatment strategies for patients with HF‐CS.

show abstract

Section: Discussionmentioning

confidence: 88%

Section: Discussionmentioning

confidence: 94%