Differences in short-term food preferences following vertical sleeve gastrectomy and Roux-en-Y gastric bypass surgery

Primeaux, Stefany D.; Tzeng, Tony H.; Allerton, Timothy D.; Chiang, Monica C.; Cosentino, Gina; Dubin, Robert L.; Varughese, Amy; Moore, Rachel; Geiselman, Paula J.; Greenway, Frank L.; Uwaifo, Gabriel I.

doi:10.1016/j.orcp.2015.09.003

Cited by 24 publications

(22 citation statements)

References 14 publications

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“…Instead, relative to controls, VSG rats selectively reduced intake when offered a palatable HFD after consuming a caloric preload. Consistent with this, clinical evidence has indicated that VSG reduces preference and liking for high‐calorie foods (rich in fat and sugar) . Taken together, these results suggest that VSG selectively abrogates hedonic feeding in the absence of a caloric need.…”

Section: Discussionsupporting

confidence: 69%

Vertical Sleeve Gastrectomy Attenuates Hedonic Feeding Without Impacting Alcohol Drinking in Rats

Sirohi

Skripnikova

Davis

2019

Obesity

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Objective Roux‐en‐Y gastric bypass surgery and vertical sleeve gastrectomy (VSG) are the most commonly performed bariatric procedures. Whereas studies report new‐onset alcohol misuse following Roux‐en‐Y gastric bypass, the impact of VSG on alcohol intake is less clear. Hedonic feeding, alcohol drinking, and hypothalamic obesity‐related gene expression following VSG were evaluated. Methods Male Long‐Evans rats underwent VSG or sham surgery. To evaluate hedonic feeding, rats received a high‐fat diet following behavioral satiation on chow. Alcohol (5%‐10% v/v) drinking was assessed in a two‐bottle choice paradigm. Finally, polymerase chain reaction array evaluated gene expression. Results VSG induced moderate but significant weight loss. Sham rats significantly escalated high‐fat diet intake following behavioral satiation, an effect significantly reduced in VSG rats. A moderate decrease in alcohol intake was observed in VSG rats at low (5%) alcohol concentration. However, overall, no significant between‐group differences were evident. Key hypothalamic orexigenic transcripts linked to stimulation of food and alcohol intake were significantly decreased in VSG rats. Conclusions VSG attenuated hedonic feeding without impacting alcohol drinking, an effect potentially mediated by alterations in genetic information flow within the hypothalamus. Importantly, these data highlight VSG as an effective bariatric procedure with a potentially reduced risk of developing alcohol use disorder.

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Section: Discussionsupporting

confidence: 69%

Vertical Sleeve Gastrectomy Attenuates Hedonic Feeding Without Impacting Alcohol Drinking in Rats

Sirohi

Skripnikova

Davis

2019

Obesity

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“…liking) of foods. As shown in two separate studies, VSG decreases the preference for high fat foods and high sugar foods [130,132]. RYGB decreases the preference for high fat foods.…”

Section: Pre-clinical Studiesmentioning

confidence: 74%

“…Several studies have investigated differences in taste perception and food preferences between different forms of bariatric surgery, (e.g. RYGB, VSG, AGB), providing evidence for surgery-dependent effects [84,128,130,131]. Furthermore, mixed results on the effects of bariatric surgery on specific tastants and preferences have been reported in clinical populations [77,127,130,132].…”

Section: Taste and Bariatric Surgery In Clinical Populationsmentioning

confidence: 99%

“…The results from this study suggests that the parallel decreases in the hedonic rating of high fat foods following VSG and RYGB may significantly decrease the intake of energy dense, high fat foods, and contribute to the observed weight loss from these two procedures. The differences on hedonic rating between the two surgeries may reflect the different anatomical approaches of the surgeries [130].…”

Section: Taste and Bariatric Surgery In Clinical Populationsmentioning

confidence: 99%

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Recent advances in the modification of taste and food preferences following bariatric surgery

Primeaux

Silva

Tzeng

et al. 2016

Rev Endocr Metab Disord

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There is a large body of evidence indicating that bariatric surgery provides durable weight loss and health benefits to patients who are obese and have comorbidities such as type 2 diabetes (T2D). However, there are still many questions related to mechanisms of metabolic improvement, predictors of success/failure, and long term consequences, which need to be answered. More recently, there has been a particular interest in the modulation of taste and food preferences that occurs after bariatric surgery and how this affects weight loss in different individuals. Animal models as well as human studies have shed some light on the role of taste in changing food preferences and how these changes may affect weight loss after surgery. The goal of this review is to discuss the physiological and behavioral consequences of bariatric surgery as a treatment for obesity and T2D, with particular emphasis on recent studies describing bariatric surgery-induced modifications in taste perception and food preferences.

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“…Ernst et al (96) also studied a group of patients who reported a reduction in consumption of desserts such as chocolates, cakes, and cookies and an increase in intake of vegetables, poultry, and protein-rich foods such as fish and eggs. Primeaux et al (235) again used verbal report by deploying a Food Preference Questionnaire and VAS comparing VSG to RYGB and found that VSG decreased the hedonic rating of most macronutrient profiles as opposed to RYGB, after which changes were more selective. Caution is needed in assessing these results because follow-up was restricted to 1-3 mo and the sample size was small.…”

Section: E Food Preferencesmentioning

confidence: 99%

Food Intake and Eating Behavior After Bariatric Surgery

Al‐Najim

Docherty

Roux

2018

Physiological Reviews

142

109

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Obesity is an escalating global chronic disease. Bariatric surgery is a very efficacious treatment for obesity and its comorbidities. Alterations to gastrointestinal anatomy during bariatric surgery result in neurological and physiological changes affecting hypothalamic signaling, gut hormones, bile acids, and gut microbiota, which coalesce to exert a profound influence on eating behavior. A thorough understanding of the mechanisms underlying eating behavior is essential in the management of patients after bariatric surgery. Studies investigating candidate mechanisms have expanded dramatically in the last decade. Herein we review the proposed mechanisms governing changes in eating behavior, food intake, and body weight after bariatric surgery. Additive or synergistic effects of both conditioned and unconditioned factors likely account for the complete picture of changes in eating behavior. Considered application of strategies designed to support the underlying principles governing changes in eating behavior holds promise as a means of optimizing responses to surgery and long-term outcomes.

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Differences in short-term food preferences following vertical sleeve gastrectomy and Roux-en-Y gastric bypass surgery

Cited by 24 publications

References 14 publications

Vertical Sleeve Gastrectomy Attenuates Hedonic Feeding Without Impacting Alcohol Drinking in Rats

Vertical Sleeve Gastrectomy Attenuates Hedonic Feeding Without Impacting Alcohol Drinking in Rats

Recent advances in the modification of taste and food preferences following bariatric surgery

Food Intake and Eating Behavior After Bariatric Surgery

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