Differences in the Surgical Outcomes of Glaucoma Surgery in Patients of African Caribbean Descent

Nagar, AM; Maghsoudlou, Panagiotis; Wormald, Richard; Barton, Keith; Hysi, Pirro G.; Ks, Lim

doi:10.1080/02713683.2022.2126859

Cited by 4 publications

(2 citation statements)

References 88 publications

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“…Also analysing the IRIS Registry, the retrospective cohort study of 79 363 eyes from Yang et al found risk factors for re‐operation after MIGS included Black race 94 . Several studies analysing the long‐term outcome of other glaucoma surgeries have also revealed non‐Caucasian and/or Black race to be more susceptible to suboptimal outcome 95–98 . Lee et al investigated the need for incisional glaucoma surgery after laser trabeculoplasty in a retrospective matched case‐comparison study and found a higher need among Black Americans 95 .…”

Section: Discussionmentioning

confidence: 99%

“…94 Several studies analysing the long-term outcome of other glaucoma surgeries have also revealed non-Caucasian and/or Black race to be more susceptible to suboptimal outcome. [95][96][97][98] Lee et al investigated the need for incisional glaucoma surgery after laser trabeculoplasty in a retrospective matched case-comparison study and found a higher need among Black Americans. 95 Analysing the long-term outcome of EX-PRESS shunt device through a retrospective cohort study of 248 eyes, Mariotti et al also identified non-Caucasian race as a risk factor for shunt failure.…”

Section: Access To Surgery and Surgical Outcomesmentioning

confidence: 99%

See 1 more Smart Citation

Social determinants of health and health disparities in glaucoma: A review

Acuff,

Wu,

Varkhedi

et al. 2024

Clinical Exper Ophthalmology

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Social determinants of health and barriers to care can significantly impact patients' access to glaucoma care and treatment, resulting in disparities within disease presentation, progression, management, and treatment outcomes. The widespread adoption of electronic health record systems has allowed researchers and clinicians to further explore these relationships, identifying factors such as race, ethnicity, and socioeconomic status to be risk factors for more severe disease and lower treatment adherence. These disparities highlight potential targets for interventions to combat these disparities and improve overall patient outcomes. This article provides a summary of the available data on health disparities within glaucoma disease presentation, progression, management, treatment, and outcomes and discusses interventions to improve care delivery and outcomes among patients with glaucoma.

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Section: Discussionmentioning

confidence: 99%

Section: Access To Surgery and Surgical Outcomesmentioning

confidence: 99%

Social determinants of health and health disparities in glaucoma: A review

Acuff,

Wu,

Varkhedi

et al. 2024

Clinical Exper Ophthalmology

View full text Add to dashboard Cite

show abstract

The reporting of equity-relevant sociodemographics in the Canadian ophthalmology literature

Bondok,

Selvakumar,

Bondok

et al. 2024

Canadian Journal of Ophthalmology

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Having Sexual Partners Lowers the Risk of Glaucoma-A Mendelian Randomization Study

Zhuang,

Zhang

2024

Preprint

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Objectives: Previous paper suggested that engaging in sexual activity exacerbated glaucoma symptoms. However, we challenge this viewpoint and designed this Mendelian randomization(MR) study to uncover the truth. Methods: To investigate the causal relationship between the two, this experiment utilized single nucleotide polymorphism(SNPs) related to "lifetime number of sexual partners" (LNSP) from the United Kingdom Biobank (UKB) and SNPs associated with glaucoma from the FinnGen Database. There were a total of 63 SNPs highly correlated with LNSP at the genome-wide significant level, which were merged with glaucoma-related SNPs. After removing their palindromic sequences, MR was conducted using the TwoSample-MR R package. Additionally, tests for heterogeneity and pleiotropy were performed using R programming. Results: In the glaucoma group, MR analysis showed: inverse variance weighted(IVW)(OR=0.758, P=0.030), MR Egger(OR=0.654,P=0.475), simple mode (OR=0.854,P=0.657), weighted median (OR=0.819, P=0.221) and weighted mode(OR=0.803,P=0.501). In the primary open angle glaucoma (POAG) group, the result showed: IVW(OR=0.897,P=0.570), MR Egger(OR=0.425, P=0.335), simple mode(OR=1.659, P=0.412), weighted median(OR=1.052, P=0.855) and weighted mode(OR=1.464,P=0.533). Heterogeneity and pleiotropy were not detected in either group. The funnel plots for both groups were relatively symmetrical. Conclusion: We reveal the truth that having sexual partners not only does not increase the overall incidence of glaucoma but, conversely, also lowers its incidence. Therefore, glaucoma patients should pursue a fulfilling sexual life with your partners with peace of mind.

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Differences in the Surgical Outcomes of Glaucoma Surgery in Patients of African Caribbean Descent

Cited by 4 publications

References 88 publications

Social determinants of health and health disparities in glaucoma: A review

Social determinants of health and health disparities in glaucoma: A review

The reporting of equity-relevant sociodemographics in the Canadian ophthalmology literature

Having Sexual Partners Lowers the Risk of Glaucoma-A Mendelian Randomization Study

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