Different antibiotic treatments for group A streptococcal pharyngitis

Driel, Mieke van; Habraken, Hilde; Meyere, Marc De

doi:10.1002/14651858.cd004406

Cited by 16 publications

(26 citation statements)

References 8 publications

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“…It has been reported that the health benefits gained from reducing complications and socioeconomic burden much outweighs the minimal risk of antibiotic treatment. Moreover, even the concern for development of antibiotic resistance is not justified since despite the large-scale use of penicillin, to date no resistant strains has yet developed [21], and even the minimum inhibitory concentrations have not changed in >70 years [60]. No doubt, that recurrent pharyngitis is a problem that requires an appropriate prophylactic antibiotic treatment, not only for its possible sequela if untreated but also for its marked global socioeconomic and health care burden.…”

Section: Discussionmentioning

confidence: 99%

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Comparative Study of Oral Daily Amoxicillin, Long Acting Intramuscular Penicillin, and Tonsillectomy in Prevention of Recurrent Pharyngitis

Ahmed¹,

Wahsh²,

Ahmed³

2015

Med-Science

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Section: Discussionmentioning

confidence: 99%

“…This is simply due to its cost effectiveness, narrow spectrum of activity and long standing proven efficacy in elimination of GABHS and prevention of rheumatic fever [20]. Furthermore, according to a recent systematic review, to date, no penicillin-resistance has been documented [21].…”

Section: Introductionmentioning

confidence: 99%

Comparative Study of Oral Daily Amoxicillin, Long Acting Intramuscular Penicillin, and Tonsillectomy in Prevention of Recurrent Pharyngitis

Ahmed¹,

Wahsh²,

Ahmed³

2015

Med-Science

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“…Narrow-spectrum penicillins are the fi rst choice for treatment because of the rarity of documented resistance to penicillin by group A streptococcus during pharyngitis treatment and because of their low cost 2,6,23 . A recent literature review failed to show differences between antibiotics in treating streptococcal pharyngitis 23 .…”

Section: Treatmentmentioning

confidence: 99%

Usefulness of Centor Score to Diagnosis of Group a Streptococcal Pharyngitis and Decision Making of Antibiotics Use

Lee¹,

Kim²,

Lee³

et al. 2018

Korean J Otorhinolaryngol-Head Neck Surg

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Acute pharyngitis/tonsillitis, which is characterized by infl ammation of the posterior pharynx and tonsils, is a common disease. Several viruses and bacteria can cause acute pharyngitis; however, Streptococcus pyogenes (also known as Lancefi eld group A β-hemolytic streptococci) is the only agent that requires an etiologic diagnosis and specifi c treatment. S. pyogenes is of major clinical importance because it can trigger post-infection systemic complications, acute rheumatic fever, and post-streptococcal glomerulonephritis. Symptom onset in streptococcal infection is usually abrupt and includes intense sore throat, fever, chills, malaise, headache, tender enlarged anterior cervical lymph nodes, and pharyngeal or tonsillar exudate. Cough, coryza, conjunctivitis, and diarrhea are uncommon, and their presence suggests a viral cause. A diagnosis of pharyngitis is supported by the patient's history and by the physical examination. Throat culture is the gold standard for diagnosing streptococcus pharyngitis. However, it has been underused in public health services because of its low availability and because of the 1-to 2-day delay in obtaining results. Rapid antigen detection tests have been used to detect S. pyogenes directly from throat swabs within minutes. Clinical scoring systems have been developed to predict the risk of S. pyogenes infection. The most commonly used scoring system is the modifi ed Centor score. Acute S. pyogenes pharyngitis is often a self-limiting disease. Penicillins are the fi rst-choice treatment. For patients with penicillin allergy, cephalosporins can be an acceptable alternative, although primary hypersensitivity to cephalosporins can occur. Another drug option is the macrolides. Future perspectives to prevent streptococcal pharyngitis and post-infection systemic complications include the development of an anti-Streptococcus pyogenes vaccine.

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“…Several attempts have recently been made to prove efficacy of shorter antibacterial therapy schemes; however, these recommendations have not gained wide acceptance [21]. Despite a steadily high GABHS cephalosporin-sensitivity, it is not advisable to use them as drugs of the first choice in view of several reasons: firstly, due to their higher cost in comparison with penicillins; secondly, due to the increased risk of antibiotic resistance formation in bacteria if cephalosporins are used [22]. Generation I-II cephalosporins may be used as an alternative therapy in patients with non-severe drug allergy to penicillins; however, they must not be used in presence of anaphylactic reactions to penicillins due to high risk of cross-sensitization [21].…”

Section: Pic 1 Acute Tonsillopharyngitis Diagnostics Algorithm For mentioning

confidence: 99%

Diagnostics and Therapy of Acute Streptococcal Tonsillopharyngitis: Modern Recommendations

2013

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Different antibiotic treatments for group A streptococcal pharyngitis

Cited by 16 publications

References 8 publications

Comparative Study of Oral Daily Amoxicillin, Long Acting Intramuscular Penicillin, and Tonsillectomy in Prevention of Recurrent Pharyngitis

Comparative Study of Oral Daily Amoxicillin, Long Acting Intramuscular Penicillin, and Tonsillectomy in Prevention of Recurrent Pharyngitis

Usefulness of Centor Score to Diagnosis of Group a Streptococcal Pharyngitis and Decision Making of Antibiotics Use

Diagnostics and Therapy of Acute Streptococcal Tonsillopharyngitis: Modern Recommendations

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