Different macaque brain network remodeling after spinal cord injury and NT3 treatment

Tian, Feng; Zhao, Chenglin; Rao, Jia‐Sheng; Guo, Xiaojun; Bao, Shu-Sheng; He, Le-Wei; Zhang, Wen; Liu, Zuxiang; Yang, Zhaoyang; Li, Xiaoguang

doi:10.1016/j.isci.2023.106784

Cited by 1 publication

(1 citation statement)

References 77 publications

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“…The functional network connections across brain regions are the basis for integrating, processing, and controlling sensorimotor information [117]. Rehabilitation exercise also regulates long-distance functional connections across brain regions, such as interhemispheric connections.…”

Section: Effect Of Rehabilitation Training On Functional Remodeling O...mentioning

confidence: 99%

Rehabilitation Training after Spinal Cord Injury Affects Brain Structure and Function: From Mechanisms to Methods

He,

Guo,

Zhao

et al. 2023

Biomedicines

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Spinal cord injury (SCI) is a serious neurological insult that disrupts the ascending and descending neural pathways between the peripheral nerves and the brain, leading to not only functional deficits in the injured area and below the level of the lesion but also morphological, structural, and functional reorganization of the brain. These changes introduce new challenges and uncertainties into the treatment of SCI. Rehabilitation training, a clinical intervention designed to promote functional recovery after spinal cord and brain injuries, has been reported to promote activation and functional reorganization of the cerebral cortex through multiple physiological mechanisms. In this review, we evaluate the potential mechanisms of exercise that affect the brain structure and function, as well as the rehabilitation training process for the brain after SCI. Additionally, we compare and discuss the principles, effects, and future directions of several rehabilitation training methods that facilitate cerebral cortex activation and recovery after SCI. Understanding the regulatory role of rehabilitation training at the supraspinal center is of great significance for clinicians to develop SCI treatment strategies and optimize rehabilitation plans.

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Section: Effect Of Rehabilitation Training On Functional Remodeling O...mentioning

confidence: 99%

Rehabilitation Training after Spinal Cord Injury Affects Brain Structure and Function: From Mechanisms to Methods

He,

Guo,

Zhao

et al. 2023

Biomedicines

Self Cite

View full text Add to dashboard Cite

show abstract

Different macaque brain network remodeling after spinal cord injury and NT3 treatment

Cited by 1 publication

References 77 publications

Rehabilitation Training after Spinal Cord Injury Affects Brain Structure and Function: From Mechanisms to Methods

Rehabilitation Training after Spinal Cord Injury Affects Brain Structure and Function: From Mechanisms to Methods

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