Different Manifestations of Rare Cases of Unruptured Sinus of Valsalva Aneurysm—Case Series and Literature Review

Abstract

Sinus of Valsalva aneurysm (SVA) is rare, and aneurysm of the left sinus of Valsalva is extremely rare cardiovascular disease. Clinical presentation can vary from mostly asymptomatic to catastrophic life-threatening emergency. We report four extremely rare cases of SVA with different manifestations of which one case involved left aortic sinus with large unruptured aneurysm causing severe mitral regurgitation (MR) and severe aortic regurgitation (AR). The second case aneurysm was from right sinus presented with trifascicular block with intermittent complete heart block (CHB). Third was a diagnosed case of unruptured right SVA and while awaiting for surgery he had sudden cardiac death (SCD) at home. Therefore, SVA can present from asymptomatic to life-threatening condition, such as SCD. To the best of our knowledge, there are individual case reports in literature, and this is the first case series of unruptured SVA in literature highlighting the rarity of this disease.

Noncoronary sinus of Valsalva aneurysm resembling a cystic cardiac mass

“…This case illustrates the confounding problem of differential diagnosis for cardiac masses. Sinus of Valsalva aneurysm (SVA) constitutes 0.5%‐3% of all congenital heart defects . Approximately 65%‐85% of SVAs originate from the right sinus of Valsalva, while SVAs originating from noncoronary (10%‐30%) and left (<5%) sinuses are very rare .…”

“…Sinus of Valsalva aneurysm (SVA) constitutes 0.5%-3% of all congenital heart defects. 1 Approximately 65%-85% of SVAs originate from the right sinus of Valsalva, while…”