Differential effect of elevated intralabyrinthine pressure on ocular vestibular evoked myogenic potentials elicited by air conducted sound and bone conducted vibration

Gürkov, Robert; Speierer, Guillaume; Wittwer, Luis; Müri, René M.; Kalla, Roger

doi:10.1016/j.clinph.2015.12.019

Cited by 4 publications

(2 citation statements)

References 21 publications

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“…In concordance with the present study, a recent report comparing ACS and BCV stimuli at 500 Hz for their dependence on ICP changes found that 500 Hz ACS oVEMP are modulated by ICP, but 500 Hz BCV oVEMP are not (Gürkov et al 2016). Fig.…”

Section: Gürkov Et Al / Ear and Hearing Vol XX No X Xxx-xxxsupporting

confidence: 93%

Effect of Elevated Intracranial Pressure on Amplitudes and Frequency Tuning of Ocular Vestibular Evoked Myogenic Potentials Elicited by Bone-Conducted Vibration

et al. 2016

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Objective:Recently, it could be demonstrated that an increased intracranial pressure causes a modulation of the air conducted sound evoked ocular vestibular evoked myogenic potential (oVEMP). The mechanism for this modulation is not resolved and may depend on a change of either receptor excitability or sound energy transmission.Design: oVEMPs were elicited in 18 healthy subjects with a minishaker delivering 500 and 1000 Hz tone bursts, in supine and tilted positions. Results:The study could confirm the frequency tuning of oVEMP. However, at neither stimulus frequency could a modulating effect of increased intracranial pressure be observed. Conclusion:These data suggest that the observed modulation of the oVEMP response by an increased intracranial pressure is primarily due to the effect of an increased intralabyrinthine pressure onto the stiffness of the inner ear contents and the middle ear-inner ear junction. Future studies on the effect of intracranial pressure on oVEMP should use airconducted sound and not bone-conducted vibration.

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Section: Gürkov Et Al / Ear and Hearing Vol XX No X Xxx-xxxsupporting

confidence: 93%

Effect of Elevated Intracranial Pressure on Amplitudes and Frequency Tuning of Ocular Vestibular Evoked Myogenic Potentials Elicited by Bone-Conducted Vibration

et al. 2016

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“…Reduction in ICP by lumbar cerebrospinal fluid (CSF) drainage has a systemic effect on VEMP amplitudes. Increasing ICP systematically alters oVEMP in terms of absolute amplitudes and frequency tuning characteristics (36)(37)(38)(39). In this report, in terms of differences in oVEMP parameters between children with EVA and those with a normal cochlea, we speculated that the presence of a third window in the inner ear labyrinth might allow for activation of vestibular receptors in LVAS patients (40).…”

Section: Discussionmentioning

confidence: 71%

Influence of Cochlear Implantation on Vestibular Function in Children With an Enlarged Vestibular Aqueduct

et al. 2021

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Background: Cochlear implantation (CI) is becoming increasingly used in the rehabilitation of hearing-impaired patients. Children with an enlarged vestibular aqueduct (EVA) need CI for severe or profound hearing loss, with excellent outcomes in hearing rehabilitation. However, vestibular function influenced by CI in children with EVA has not been clarified. We compared the characteristics of vestibular function in implanted children with EVA and those with a normal cochlea.Methods: In this retrospective case-control study, 16 children with large vestibular aqueduct syndrome (LVAS) and 16 children with a normal cochlea were recruited as the Study and Control Group, respectively. All children (mean age, 10.3 ± 4.4 years) had bilateral profound sensorineural hearing loss (SNHL) and normal pre-operative vestibular functions and underwent unilateral CI. Otolith and canal functions were assessed before CI and 12 months thereafter. Cervical vestibular-evoked myogenic potential (cVEMP), ocular vestibular-evoked myogenic potential (oVEMP), and video head impulse test (vHIT) were evaluated.Results: Full insertion of the electrode array was achieved in all the cases. Preoperatively, no significant differences in parameters in cVEMP between the Study and Control Group were revealed (p > 0.05). In pre-operative oVEMP, shorter N1 latencies (p = 0.012), shorter P1 latencies (p = 0.01), and higher amplitudes (p = 0.001) were found in the Study than in the Control Group. The Study Group had shorter P1 latency in cVEMP (p = 0.033), and had lower amplitude in oVEMP after implantation (p = 0.03). Statistically significant differences were not found in VOR gains of all three semicircular canals before and after surgery (p > 0.05). VEMP results revealed that the Control Group had significantly lower deterioration rates after CI (p < 0.05). The surgical approach and electrode array had no statistically significant influence on the VEMP results (p > 0.05).Conclusion: oVEMP parameters differed between children with EVA and children with a normal cochlea before surgery. Systematic evaluations before and after CI showed that otolith function was affected, but all three semicircular canals functions were essentially undamaged after implantation. In contrast to subjects with a normal cochlea, children with EVA are more likely to preserve their saccular and utricular functions after CI surgery. Possible mechanisms include less pressure-related damage, a reduced effect in terms of the air-bone gap (ABG), or more sensitivity to acoustic stimulation.

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Idiopathic intracranial hypertension: Ocular vestibular evoked myogenic potentials as a new evaluation tool

Gürkov

Wittwer

Speierer

et al. 2017

Clinical Neurophysiology

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Differential effect of elevated intralabyrinthine pressure on ocular vestibular evoked myogenic potentials elicited by air conducted sound and bone conducted vibration

Cited by 4 publications

References 21 publications

Effect of Elevated Intracranial Pressure on Amplitudes and Frequency Tuning of Ocular Vestibular Evoked Myogenic Potentials Elicited by Bone-Conducted Vibration

Effect of Elevated Intracranial Pressure on Amplitudes and Frequency Tuning of Ocular Vestibular Evoked Myogenic Potentials Elicited by Bone-Conducted Vibration

Influence of Cochlear Implantation on Vestibular Function in Children With an Enlarged Vestibular Aqueduct

Idiopathic intracranial hypertension: Ocular vestibular evoked myogenic potentials as a new evaluation tool

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