Differential expression and intrachromosomal evolution of the sghC1q genes in zebrafish (Danio rerio)

RNA-seq analysis of mucosal immune responses reveals signatures of intestinal barrier disruption and pathogen entry following Edwardsiella ictaluri infection in channel catfish, Ictalurus punctatus

“…Indicative of shared mucosal immune responses to fish pathogens, we observed sharp down-regulation of tumor suppressor protein p53 gene at 24 h and 3 d following infection similar to results reported in gills of amoebic gill disease-affected Atlantic salmon [10]. Some innate immune factors known to be up-regulated in response to fish pathogens, were also observed to be down-regulated here, including C1q-like genes [62]; neurotoxin/CD59-like [10,63]; liverexpressed antimicrobial peptide 2 (LEAP-2) [64]; and serum amyloid P [65].…”