Diffuse Metastases in Bronchial Cancer

Densert, O.; Söderström, Jan

doi:10.1111/apm.1965.64.4.477

Cited by 6 publications

(5 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Excluding the melanocarcinomas, all of the 17 cases of intrasinusoidal liver carcinoma reported by Smith (1961) were undifferentiated tumours, and this correlates well with the work of Densert and Soderstrom (1965), who reviewed diffuse metastases from primary bronchogenic carcinoma to the liver and spleen in a necropsy series. These workers found an overall incidence of 2.6 % of diffuse liver involvement but this occurred only with 'smallcelled' types of bronchial carcinoma.…”

Section: Discussionsupporting

confidence: 76%

Cor pulmonale due to tumour embolism derived from intrasinusoidal metastatic liver carcinoma.

Burnett¹

1975

J Clin Pathol

View full text Add to dashboard Cite

SYNOPSIS Two cases of primary breast carcinoma are described, both terminating in acute cardiorespiratory failure due to multiple tumour micro-embolism. In both cases the source of the emboli was extensive metastatic intrasinusoidal carcinomatous infiltration of the liver. The association of these two uncommon conditions has not previously been reported. A brief review of the literature pertaining to diffuse intrasinusoidal metastatic carcinoma of the liver and to carcinomatous pulmonary embolism is included. The latter condition may be commoner and of greater clinical significance than has hitherto been appreciated. Some of the factors which may be responsible for this peculiar type of tumour dissemination are discussed.

show abstract

Section: Discussionsupporting

confidence: 76%

Cor pulmonale due to tumour embolism derived from intrasinusoidal metastatic liver carcinoma.

Burnett¹

1975

J Clin Pathol

View full text Add to dashboard Cite

show abstract

“…Small cell lung cancer has been recognized to be the most common cell type likely to metastasize to the spleen and squamous cell lung carcinoma the least likely (3,4). In our previous study of lung cancer metastasis, adenocarcinoma had almost the same frequency of spleen metastasis as small cell lung cancer (1.3 vs. 2.0%, respectively), while in squamous cell carcinoma, only 0.6% of patients developed spleen metastasis (18).…”

Section: A B Cmentioning

confidence: 82%

“…The incidence of spleen metastasis is considered to differ among histologic types of lung cancer (3,4,18). Small cell lung cancer has been recognized to be the most common cell type likely to metastasize to the spleen and squamous cell lung carcinoma the least likely (3,4).…”

Section: A B Cmentioning

confidence: 99%

See 1 more Smart Citation

Isolated spleen recurrence in a patient with lung adenocarcinoma: A case report

Iguchi

Ishibashi

Kondo

et al. 2015

Experimental and Therapeutic Medicine

View full text Add to dashboard Cite

Abstract. Spleen metastasis is extremely rare in patients with lung cancer. However, recent improvements in imaging modalities may enable the antemortem diagnosis of spleen metastasis. The present study reports the case of a female patient with lung adenocarcinoma and spleen metastasis. The patient developed isolated spleen metastasis in the postoperative course. This rare metastasis was detected in a follow-up abdominal computed tomography (CT) scan without any symptoms, and was confirmed by fluorodeoxyglucose positron emission tomography (FDG-PET)/CT scan. Although very rare, chest physicians and thoracic surgeons should be alert to the possibility of spleen metastasis development when evaluating the follow-up abdominal CT scan. FDG-PET/CT scanning and an interventional approach should be considered to clarify the possibility of spleen metastasis.

show abstract

“…The most common histopathological subtype of lung cancer with isolated splenic metastasis was adenocarcinoma (44% of cases), followed by squamous cell cancer (17% of cases) and large-cell lung cancer (17% of cases). Surprisingly, there is no report of isolated splenic metastasis in small-cell lung cancer, although splenic metastasis in the context of multiple metastatic sites is well recognized in small-cell lung cancer [ 12 , 13 , 14 ]. One case of carcinoid with isolated spleen deposits has been reported.…”

Section: Discussionmentioning

confidence: 99%

Isolated Splenic Metastasis from Non-Small-Cell Lung Cancer: A Case Report and Review of the Literature

et al. 2017

View full text Add to dashboard Cite

Metastases to the spleen are rare but have been reported for different tumor entities, including breast cancer, lung cancer, colorectal cancer, ovarian cancer, and melanoma. As an isolated event, splenic metastasis from non-small-cell lung cancer (NSCLC) is exceedingly rare. Until now, only 28 cases have been reported in the medical literature. We report the case of a 66-year-old woman with NSCLC (adenocarcinoma) who presented with a synchronous, isolated splenic metastasis. Operative removal of both primary tumor and metastasis was not possible due to multiple comorbidities. Therefore, treatment was limited to combined systemic chemotherapy and simultaneous radiation of the primary tumor, which led to partial remission of the disease. Isolated metastasis to the spleen in NSCLC has been reported only 28 times in the medical literature, most often in male patients with right-sided lung tumors, most of which were adenocarcinomas. The majority of patients were asymptomatic with respect to splenic metastasis. About half of the reported cases were isolated metachronous splenic metastases. Splenectomy seems to confer a survival advantage. We review the pertinent medical literature.

show abstract

Diffuse Metastases in Bronchial Cancer

Cited by 6 publications

References 19 publications

Cor pulmonale due to tumour embolism derived from intrasinusoidal metastatic liver carcinoma.

Cor pulmonale due to tumour embolism derived from intrasinusoidal metastatic liver carcinoma.

Isolated spleen recurrence in a patient with lung adenocarcinoma: A case report

Isolated Splenic Metastasis from Non-Small-Cell Lung Cancer: A Case Report and Review of the Literature

Contact Info

Product

Resources

About