Diffuse Unilateral Subacute Neuroretinitis in Europe

Harto, M; Rodriguez-Salvador, Vicente; Aviño, J.; Duch-Samper, A.; Menezo, J.L.

doi:10.1177/112067219900900109

Cited by 20 publications

(10 citation statements)

References 13 publications

(22 reference statements)

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“…Cases of DUSN have been reported in several countries including Brazil, Venezuela, USA, Canada, Caribbean, Spain, Germany, Senegal and India [1,3,[6][7][8][9][10]. To our knowledge, our two cases are the first from the UK that have been reported in the literature to be successfully treated with albendazole.…”

Section: Introductionsupporting

confidence: 39%

Diffuse unilateral subacute neuroretinitis in the United Kingdom

2010

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We describe the first two cases of diffuse unilateral subacute neuroretinitis (DUSN) in the UK successfully treated with albendazole. Two patients are described who presented with unilateral reduction in vision, with clusters of yellow-white retinal lesions fading and reappearing in new locations of the fundus over a period of weeks. Based on the clinical picture, the diagnosis of DUSN was made, even though no subretinal worm could be found. Both patients were treated with albendazole 400 mg daily for 30 days. After 4 weeks the vision in the affected eye improved to 6/9 in each patient and the retinal lesions resolved completely. Over a follow-up period of 28 months and 13 months respectively, there was no recurrence of any lesion and the vision was maintained. DUSN is a sight-threatening disease and the preservation of vision relies on early diagnosis and treatment. Laser photocoagulation of the worm is the treatment of choice, but this was not possible in either case, as no worm could be found; however, oral albendazole proved to be a safe and effective alternative treatment.

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Section: Introductionsupporting

confidence: 39%

Diffuse unilateral subacute neuroretinitis in the United Kingdom

2010

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“…34,35 DUSN is most prevalent in the southeastern United States and the Caribbean, although some cases have been reported in many sections of the United States, Canada, the northern part of South America, Europe, and China. [36][37][38][39][40][41] In the United States, DUSN is probably caused by at least two different nematodes. The smaller one, Ancylostoma caninum, measures between 400 and 1,000 µm in length and has a diameter of approximately one-twentieth of its length.…”

Section: Treatmentmentioning

confidence: 99%

Ocular Parasitic Diseases: A Review on Toxocariasis and Diffuse Unilateral Subacute Neuroretinitis

Cortez¹,

Ramírez²,

Collet³

et al. 2011

J Pediatr Ophthalmol Strabismus

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Parasitic infections may damage various ocular tissues, thereby causing visual dysfunction. In 1950, Wilder described the first case in which larval forms of nematodal intestinal roundworms (Ascaridoidea: Ascaris, Toxocara, Ancylostoma, Necator, and Strongyloides) were implicated as a cause of intraocular disease. This review focuses on two disorders associated with parasitic infections: ocular toxocariasis and diffuse unilateral subacute neuroretinitis.

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“…70,76 Its occurrence has been described also in the Caribbean, 9 Canada, 83 Germany, 84 Spain, 85 China, 86 and India. 70,76 Its occurrence has been described also in the Caribbean, 9 Canada, 83 Germany, 84 Spain, 85 China, 86 and India.…”

Section: Epidemiologymentioning

confidence: 99%

“…86.6). Cases of nematodes infesting both eyes 89 or two nematodes infesting the same eye 85 are less frequently reported. In the typical disease only one eye is affected and a single motile subretinal nematode can be identified.…”

Section: Epidemiologymentioning

confidence: 99%