Diffusion-Weighted Imaging in Neonates

Rodrigues, K M; Grant, P. Ellen

doi:10.1016/j.nic.2011.01.012

Cited by 21 publications

(8 citation statements)

References 50 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, the sensitivity of DWI to the acute phase of edema is superior to that of ultrasound and conventional MRI, especially in the immature brain27). Conventional MRI techniques are insensitive to acute edema in the newborn brain due to the lack of myelination in neonates28). DWI with corresponding apparent diffusion coefficient maps can detect acute edema earlier and more clearly28).…”

Section: Clinical Characteristics Of Rotavirus-associated Wmi In Newbmentioning

confidence: 99%

“…Conventional MRI techniques are insensitive to acute edema in the newborn brain due to the lack of myelination in neonates28). DWI with corresponding apparent diffusion coefficient maps can detect acute edema earlier and more clearly28). According to Yeom et al11), if DWI had not been performed, the unique pattern of WMI might not have been recognized because only subtle signal changes were detected in most of their patients evaluated by conventional MRI techniques (Fig.…”

Section: Clinical Characteristics Of Rotavirus-associated Wmi In Newbmentioning

confidence: 99%

See 1 more Smart Citation

White matter injury following rotavirus infection in neonates: new aspects to a forgotten entity, 'fifth day fits'?

Yeom

Park

2016

Korean J Pediatr

View full text Add to dashboard Cite

That rotavirus infection can cause neurological symptoms in young children has been well established. However, it is surprising why rotavirus infection has been overlooked as a cause of neonatal seizures for many years, despite significant research interest in neonatal rotavirus infection. Neonates are the age group most vulnerable to seizures, which are typically attributed to a wide range of causes. By contrast, because rotavirus infection is usually asymptomatic, it has been difficult to identify an association between this virus and neonatal seizures. The conventional wisdom has been that, although neonates are commonly infected with rotavirus, neurological complications are rare in this age. However, recent studies using diffusion-weighted imaging (DWI) have suggested a connection between rotavirus infection and neonatal seizures and that rotavirus infection can induce diffuse white matter injury without direct invasion of the central nervous system. The clinical features of white matter injury in rotavirus-infected neonates include the onset of seizures at days 4–6 of life in apparently healthy term infants. The recent findings seem to contradict the conventional wisdom. However, white matter injury might not be a completely new aspect of rotavirus infection in neonates, considering the forgotten clinical entity of neonatal seizures, 'fifth day fits'. With increased use of DWI in neonatal seizures, we are just starting to understand connection between viral infection and white matter injury in neonates. In this review, we discuss the historical aspects of rotavirus infection and neonatal seizures. We also present the clinical features of white matter injury in neonatal rotavirus infection.

show abstract

Section: Clinical Characteristics Of Rotavirus-associated Wmi In Newbmentioning

confidence: 99%

Section: Clinical Characteristics Of Rotavirus-associated Wmi In Newbmentioning

confidence: 99%

White matter injury following rotavirus infection in neonates: new aspects to a forgotten entity, 'fifth day fits'?

Yeom

Park

2016

Korean J Pediatr

View full text Add to dashboard Cite

show abstract

“…15 However, DWI with corresponding ADC maps can detect acute edema earlier and more clearly than conventional MRI techniques. MRI was performed between 1 and 10 days after the onset of seizures (median 2 days, interquartile range 1-3 days).…”

mentioning

confidence: 99%

Distinctive pattern of white matter injury in neonates with rotavirus infection

et al. 2015

View full text Add to dashboard Cite

show abstract

“…Standard neonatal brain MR imaging protocols utilize T1-and T2-weighted sequences in multiple planes, which are satisfactory for defining anatomic abnormalities, and diffusion weighting in the axial plane offering important information in cases of ischemic insults and posterior fossa tumors [34,35]. MR imaging is also critical for intraoperative guidance during tumor resection [36].…”

Section: Postnatal Imagingmentioning

confidence: 99%