Diffusion-Weighted Imaging of the Head and Neck in Healthy Subjects: Reproducibility of ADC Values in Different MRI Systems and Repeat Sessions

Kolff-Gart, A.S.; Pouwels, Petra J. W.; Noij, Daniel P.; Ljumanović, Redina; Vandecaveye, Vincent; Keyzer, Frederik De; Bree, Remco de; Graaf, Pim de; Knol, Dirk L.; Castelijns, Jonas A.

doi:10.3174/ajnr.a4114

Cited by 68 publications

(42 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Hence studies assessing reproducibility of head and neck tissue [126,147,148] were also included in this review. Some studies used vendorindependent post-processing software packages to compute the ADC maps [56,125,126,137,140,148] while others used site-specific software packages either vendorspecific or locally developed [68,138,141,147] . Although some investigators demonstrated high variability in the measured ADC (27.1% for left liver lobe) with vendorindependent software packages [56] , others found less variability in the measured ADC using vendor-specific software [148] .…”

Section: Discussionmentioning

confidence: 99%

Diffusion-weighted magnetic resonance imaging in cancer: Reported apparent diffusion coefficients,in-vitroandin-vivoreproducibility

Jafar

Parsaï

Miquel

2016

WJR

View full text Add to dashboard Cite

There is considerable disparity in the published apparent diffusion coefficient (ADC) values across different anatomies. Institutions are increasingly assessing repeatability and reproducibility of the derived ADC to determine its variation, which could potentially be used as an indicator in determining tumour aggressiveness or assessing tumour response. In this manuscript, a review of selected articles published to date in healthy extracranial body diffusion-weighted magnetic resonance imaging is presented, detailing reported ADC values and discussing their variation across different studies. In total 115 studies were selected including 28 for liver parenchyma, 15 for kidney (renal parenchyma), 14 for spleen, 13 for pancreatic body, 6 for gallbladder, 13 for prostate, 13 for uterus (endometrium, myometrium, cervix) In addition, six phantom studies and thirteen in vivo studies were summarized to compare repeatability and reproducibility of the measured ADC. All selected phantom studies demonstrated lower intra-scanner and inter-scanner variation compared to in vivo studies. Based on the findings of this manuscript, it is recommended that protocols need to be optimised for the body part studied and that system-induced variability must be established using a standardized phantom in any clinical study. Reproducibility of the measured ADC must also be assessed in a volunteer population, as variations are far more significant in vivo compared with phantom studies. Core tip: Diffusion-weighted magnetic resonance imaging was highlighted as a potential cancer imaging biomarker by a team of experts in a report published in 2009. We review the variability of published diffusion values in the major extra-cranial organs and focus on the validation literature, both in vivo and in vitro . A total of 115 studies were selected including for liver parenchyma, kidney, pancreatic body, spleen, gallbladder, prostate, uterus (endometrium, myometrium, cervix) and breast. We also look in detail at the published repeatability and reproducibility studies, both in vivo and in phantoms. A series of recommendations based on our findings are given at the end of this review.Jafar MM, Parsai A, Miquel ME. Diffusion-weighted magnetic resonance imaging in cancer: Reported apparent diffusion coefficients, in vitro and in vivo reproducibility.

show abstract

Section: Discussionmentioning

confidence: 99%

Diffusion-weighted magnetic resonance imaging in cancer: Reported apparent diffusion coefficients,in-vitroandin-vivoreproducibility

Jafar

Parsaï

Miquel

2016

WJR

View full text Add to dashboard Cite

show abstract

“…The mean ADC of the pons (1.12-1.14 ×10 -3 mm 2 /s) calculated in our study was also higher than the mean ADC value established for pons (0.7 ×10 -3 mm 2 ). It has been previously reported that non-echoplanar DWI techniques yield different ADC values than echoplanar techniques (33).…”

Section: Discussionmentioning

confidence: 99%

Accuracy of turbo spin-echo diffusion-weighted imaging signal intensity measurements for the diagnosis of cholesteatoma

Özgen

Bulut²,

Dolgun³

et al. 2017

Diagn Interv Radiol

View full text Add to dashboard Cite

“…In a given magnetic field a higher b value will result in a lower ADC. Another factor is variation in MRI scanners; a phantom study has shown that ADC values varied significantly across different MRI systems (27). Furthermore, the surrounding structure may also influence the ADC measurements, which is why multiple measurements were performed in our study to increase the accuracy.…”

Section: Discussionmentioning

confidence: 99%

Role of diffusion-weighted imaging for detecting bone marrow infiltration in skull in children with acute lymphoblastic leukemia

Cao

Liang

Gen³

et al. 2016

Diagn Interv Radiol

View full text Add to dashboard Cite

Diffusion-Weighted Imaging of the Head and Neck in Healthy Subjects: Reproducibility of ADC Values in Different MRI Systems and Repeat Sessions

Cited by 68 publications

References 23 publications

Diffusion-weighted magnetic resonance imaging in cancer: Reported apparent diffusion coefficients,in-vitroandin-vivoreproducibility

Diffusion-weighted magnetic resonance imaging in cancer: Reported apparent diffusion coefficients,in-vitroandin-vivoreproducibility

Accuracy of turbo spin-echo diffusion-weighted imaging signal intensity measurements for the diagnosis of cholesteatoma

Role of diffusion-weighted imaging for detecting bone marrow infiltration in skull in children with acute lymphoblastic leukemia

Contact Info

Product

Resources

About