Digital Breast Tomosynthesis Versus Additional Diagnostic Mammographic Views for the Evaluation of Asymmetric Mammographic Densities

Waheed, Hira; Masroor, Imrana; Afzal, Shaista; Alvi, Muhammad Ismail; Jahanzeb, Syed

doi:10.7759/cureus.9637

Cited by 4 publications

(3 citation statements)

References 19 publications

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“…On the contrary, a few additional magnification and spot compression views were required after using DBT. Although we do not measure the statistical significance of this descriptive finding, this finding was consistent with prior studies (68). According to this result, we could suggest that DBT may be considered as a substitute for additional mammographic views.…”

Section: Discussionsupporting

confidence: 85%

The ability of digital breast tomosynthesis to reduce additional examinations in older women

Gharaibeh,

Alfwares,

Elobeid

et al. 2023

Front. Med.

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AimsTo assess the diagnostic performance of digital breast tomosynthesis (DBT) in older women across varying breast densities and to compare its effectiveness for cancer detection with 2D mammography and ultrasound (U/S) for different breast density categories. Furthermore, our study aimed to predict the potential reduction in unnecessary additional examinations among older women due to DBT.MethodsThis study encompassed a cohort of 224 older women. Each participant underwent both 2D mammography and digital breast tomosynthesis examinations. Supplementary views were conducted when necessary, including spot compression and magnification, ultrasound, and recommended biopsies. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and area under the curve (AUC) were calculated for 2D mammography, DBT, and ultrasound. The impact of DBT on diminishing the need for supplementary imaging procedures was predicted through binary logistic regression.ResultsIn dense breast tissue, DBT exhibited notably heightened sensitivity and NPV for lesion detection compared to non-dense breasts (61.9% vs. 49.3%, p < 0.001) and (72.9% vs. 67.9%, p < 0.001), respectively. However, the AUC value of DBT in dense breasts was lower compared with non-dense breasts (0.425 vs. 0.670). Regarding the ability to detect calcifications, DBT demonstrated significantly improved sensitivity and NPV in dense breasts compared to non-dense breasts (100% vs. 99.2%, p < 0.001) and (100% vs. 94.7%, p < 0.001), respectively. On the other hand, the AUC value of DBT was slightly lower in dense breasts compared with non-dense (0.682 vs. 0.711). Regarding lesion detection for all cases between imaging examinations, the highest sensitivity was observed in 2D mammography (91.7%, p < 0.001), followed by DBT (83.7%, p < 0.001), and then ultrasound (60.6%, p < 0.001). In dense breasts, sensitivity for lesion detection was highest in 2D mammography (92.9%, p < 0.001), followed by ultrasound (76.2%, p < 0.001), and the last one was DBT. In non-dense breasts, sensitivities were 91% (p < 0.001) for 2D mammography, 50.7% (p < 0.001) for ultrasound, and 49.3% (p < 0.001) for DBT. In terms of calcification detection, DBT displayed significantly superior sensitivity compared to 2D mammography in both dense and non-dense breasts (100% vs. 91.4%, p < 0.001) and (99.2% vs. 78.5%, p < 0.001), respectively. However, the logistic regression model did not identify any statistically significant relationship (p > 0.05) between DBT and the four dependent variables.ConclusionOur findings indicate that among older women, DBT does not significantly decrease the requirement for further medical examinations.

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Section: Discussionsupporting

confidence: 85%

The ability of digital breast tomosynthesis to reduce additional examinations in older women

Gharaibeh,

Alfwares,

Elobeid

et al. 2023

Front. Med.

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“…35 DBT has been found at least equivalent to additional imaging views, especially for the mammographically detected asymmetric densities. 40,41 Use of DBT leads to decreased need of additional views for noncalcified findings and can also reduce the use of ultrasound and biopsy 42 (Figure 5).…”

Section: Triangulationmentioning

confidence: 99%

Digital Breast Tomosynthesis: Potential Benefits in Routine Clinical Practice

2021

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Digital breast tomosynthesis (DBT) is gradually being implemented in routine clinical breast imaging practice. The technique of image acquisition reduces the confounding effect of overlapping breast tissue, which substantially affects cancer detection, abnormal recall, and interval cancer rates in a screening/ surveillance setting. In a diagnostic setting, tomosynthesis also allows for improved lesion localization and characterization over conventional imaging, which potentially improves the accuracy and improved workflow efficiency. To optimize the utility of tomosynthesis, imagers should be aware of the pertinent aspects of image acquisition as it relates to interpretation, the appearance of benign and malignant pathologies, and sources of possible misinterpretation. This article aims to provide a practical knowledge base of DBT and demonstrate its potential benefits when incorporated into routine clinical practice.

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“…Daha nadir olarak memeye spesifik tomografi ve pozitron emisyon tomografisinin kullanıldığını belirten çalışmalar mevcuttur (3). Mamografi meme kanserinde altın standart olarak kabul edilen ve mortaliteyi azalttığı kanıtlanmış tarama yöntemidir (4). Konvansiyonel ve dijital mamografinin duyarlılığı yağ doku ağırlıklı meme parankiminde yüksek iken, dens memelerde tanısal duyarlılık azalmaktadır (5).…”

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Fokal Asimetrik Meme Dansitelerinin Değerlendirilmesinde Tomosentezin Tanıya Katkısı

Guclu

Naldemir

Ünlü

et al. 2023

Sağlık Bilimlerinde Değer

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Amaç: Bu çalışma ile mamografik incelemelerde fokal asimetrik dansite saptanan ve ek tetkik gerektiren olgularda tomosentezin tanıya katkısını araştırmak amaçlanmıştır. Gereç ve Yöntemler: Hastanemiz Radyoloji Anabilim Dalı Meme Görüntüleme Ünitesine Şubat 2020-Haziran 2022 tarihleri arasında tarama ya da tanısal amaçlı dijital mamografi tetkiki yapılan ve fokal asimetrik meme dansitesi saptanan 56 olguya, ek olarak tomosentez inceleme yapıldı ve bulgular BI-RADS kullanılarak sınıflandırıldı. Hasta yaşı, meme paterni, fokal asimetik dansite bulunan meme ve kadranı kaydedildi. Sonrasında tamamlayıcı ve altın standart tetkik olarak bilateral meme ultrasonografi incelemesi yapılarak bulgular kaydedildi. Bulgular: Dijital mamografi görüntüleme sonucunda fokal asimetrik dansite nedeniyle BI-RADS 0 olarak değerlendirilen 56 kadın olgunun ortalama yaşları 51,5 ± 8,1’dir. %12,5’i (n=7) A tipi, %42,9’u (n=24) B tipi, %41,1’i (n=23) C tipi, %3,6’sı (n=2) D tipi meme paternine sahiptir. Fokal asimetrik dansitelerin % 44,6’sı (n=25) sağ, %55,4’ü (n=31) sol memede saptanmıştır. Dijital tomosentez incelemelerinin değerlendirilmesinde, olguların % 41,1’i (n=23) BI-RADS 1, % 16,1’i (n=9) BI-RADS 2, % 21,4’ü (n=12) BI-RADS 3, 21,4’ü (n=12) BI-RADS 4 olarak sınıflanmıştır. Ultrasonografik incelemede hastaların %42,9’u (n=24) asimetrik fibroglandüler doku, %17,9’u (n=10) olası benign lezyon, % 19,6’sı (n=11) ise malign lezyon olarak değerlendirilmiştir. Histopatolojik inceleme önerilen 12 hastanın ikisi stromal fibrozis, diğer 10’u ise biri lobüler olmak üzere invaziv meme karsinomu olarak değerlendirilmiştir. Sonuç: Bu çalışma mamografik incelemeler ile morfolojisi değerlendirilemeyen ve ek tetkik gerektiren fokal asimetrik dansitelerde tomosentezin tanısal önemini vurgulamaktadır. Tomosentez, son dekatta kullanımı giderek artan ve parankime süperpoze lezyonlarda yaşanabilecek tanı güçlüklerini çözebilecek görece yeni bir tekniktir.

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Digital Breast Tomosynthesis Versus Additional Diagnostic Mammographic Views for the Evaluation of Asymmetric Mammographic Densities

Abstract: Open Access Original Article

Cited by 4 publications

References 19 publications

The ability of digital breast tomosynthesis to reduce additional examinations in older women

The ability of digital breast tomosynthesis to reduce additional examinations in older women

Digital Breast Tomosynthesis: Potential Benefits in Routine Clinical Practice

Fokal Asimetrik Meme Dansitelerinin Değerlendirilmesinde Tomosentezin Tanıya Katkısı

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