Digital microscopic mapping of laser induced polarization ellipticity maps in differential diagnostics of preparations of benign and malignant prostate tumours

Optical Sensor System for 3D Jones Matrix Reconstruction of Optical Anisotropy Maps of Self-Assembled Polycrystalline Soft Matter Films

“…The resulting set of optical anisotropy maps was analyzed in a statistical approach using the following algorithms to calculate mean ( ), variance ( ), skewness ( ) and kurtosis ( ) [ 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 ] where —CCD pixels quantity.…”

“…Polarimetric studies of the polarization manifestations of BF anisotropy make it possible to detect pathological changes in the quaternary and tertiary polycrystalline structure of basic proteins (albumin and globulin) in blood plasma and other biological fluids, which are inaccessible in the most common biochemical methods. In a series of works [ 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 ], the sensitivity of polarimetric methods to inflammatory, pathological and necrotic changes in the polycrystalline structure of films of blood plasma, urine, synovial fluid, and cerebrospinal fluid was demonstrated.…”

“…This polarimetric approach can be developed and generalized into a synthesis of polarization interference mapping and digital holographic reconstruction of object fields of complex amplitudes for layer-by-layer reconstruction of optical anisotropy maps of dehydrated BF films. Therefore, to improve the sensitivity and accuracy of polarimetric matrix diagnostics, it is urgent to create a new method for the layer-by-layer study of polycrystalline films of biological fluids by synthesizing polarization (Jones matrix) and interference methods [ 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 ].…”