Dilute solution properties of some polycarboxybetaines with antibacterial activity

Grigoras, Anca Giorgiana; Racoviţă, Stefania; Vasiliu, Silvia; Nistor, Manuela T.; Dunca, Simona; Bărboiu, Virgil; Grigoraş, Vasile Cristian

doi:10.1007/s10965-012-0008-1

Cited by 14 publications

(4 citation statements)

References 42 publications

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“…They are usually dissolved in aqueous solution in the presence of excessive salts. [20][21][22][23][24] Poly[1-(3-sulphopropyl) betaine-2-vinylpyridinium] (PSB) is one of rare polyzwitterions dissolved in water, [25][26][27] which makes the study on polyzwitterions in saltfree and low-salt solutions possible.…”

Section: Introductionmentioning

confidence: 99%

Dynamics of polyzwitterions in salt-free and salt solutions

Cao

Zhang

2015

Phys. Chem. Chem. Phys.

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Dynamics of polyzwitterions remains largely unclear. We have prepared zwitterionic poly[1-(3-sulphopropyl) betaine-2-vinylpyridinium] (PSB) and investigated its dynamics in aqueous solution as a function of added salt (NaCl) concentration (Cs) by dynamic laser light scattering (DLS) and sedimentation velocity (SV) in analytical ultracentrifugation (AUC). A fast and a slow mode can be observed by DLS in a salt-free and low-salt solution, where the latter exhibits a maximum intensity at Cs ∼ 10(-3) M. SV measurements demonstrate that the fast mode corresponds to the diffusion of individual chains and the slow mode arises from the dynamic inhomogeneity due to interchain electrostatic repulsion. As Cs increases, the sedimentation coefficient exhibits a maximum at Cs ∼ 0.1 M whereas the diffusion coefficient has a minimum at Cs ∼ 10(-3) M and a maximum at Cs ∼ 0.1 M. Namely, PSB shows a complex dynamics in a salt-free and low-salt solution and anti-polyelectrolyte behavior in a high-salt solution. Our studies reveal that the dynamics of polyzwitterions is mediated by the long range interchain electrostatic repulsion and short range intrachain attraction, which are determined by effective charges on the chains.

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Section: Introductionmentioning

confidence: 99%

Dynamics of polyzwitterions in salt-free and salt solutions

Cao

Zhang

2015

Phys. Chem. Chem. Phys.

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“…The unfractionated samples were analyzed by differential refractometry and multiangle laser light scattering methods following a well known protocol [17,18]. An Optilab-rEX differential refractometer (Wyatt Tech.…”

Section: Experimental Part Materials and Methodsmentioning

confidence: 99%

Solubility Behaviour of Cellulose Acetate Butyrate in Mixture of Solvents

Grigoras¹,

Olaru²

2017

Rev. Chim.

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In order to identify the proper solvent mixture for future processing from solution of cellulose derivatives, the laser light scattering method was used. The multiangle laser light scattering parameters of macromolecular chains in solution (weight-average molecular weigh , radius of gyration Rg and second virial coefficient A2) were correlated with the values of dielectric constant of solvent mixture (2-methoxyethanol + N,N-dimethylformamide). The experimental results revealed that the protic solvent favored the extended conformation of the macromolecules in solution, necessary condition to obtaine nanofibers by electrospinning.

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“…The bacteria were preincubated for 18 h at 37 C. For each bacterial strain, 3 mL of suspension with about 10 7 CFU 35 and disinfected steel discs were placed on the agar surface. Circular films, 10 mm in diameter and 100 mm thick, were introduced in the disks.…”

Section: Antimicrobial Activitymentioning

confidence: 99%

Biocidal activity of cellulose materials for medical implants

Onofrei¹,

Dobos²,

Dunca

et al. 2015

J of Applied Polymer Sci

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Surface wettability trends, and blood component adhesion of some cellulose acetate phthalate/hydroxypropyl cellulose blend films are analyzed in view of adapting the system to biomedical applications. The results show that intermediate blend compositions of the corresponding films influence the surface tension parameters-controlled by the interactions occurring in the system. Increasing hydrophobicity and, implicitly, decreasing the polar surface tension components, are correlated with the adhesion/cohesion of blood components and plasma proteins. Thus, the work of spreading proteins on the hydrophobic blend surfaces indicated that albumin is not absorbed preferentially, while fibrinogen is characterized by a higher degree of adhesion on the surfaces, and also that selective adsorption of plasma proteins modifies blood compatibility. In addition, the obtained results and the ascertained antimicrobial activity of the studied blends contribute to the development of new applications in the biomedical field.

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Dilute solution properties of some polycarboxybetaines with antibacterial activity

Cited by 14 publications

References 42 publications

Dynamics of polyzwitterions in salt-free and salt solutions

Dynamics of polyzwitterions in salt-free and salt solutions

Solubility Behaviour of Cellulose Acetate Butyrate in Mixture of Solvents

Biocidal activity of cellulose materials for medical implants

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