Dioxin-like compounds (DLCs) in the environment and their impact on human health

Walosik, Alicja; Żeber–Dzikowska, Ilona; Szajner, Jarosław; Dziechciaż, Małgorzata; Pawlas, Natalia; Czarny-Działak, Małgorzata

doi:10.5601/jelem.2021.26.2.2130

Cited by 2 publications

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“…Dioxins are extremely harmful substances that are released into the environment as byproducts of industrial processes such burning plastic and medical waste, bleaching paper with chlorine, and producing certain pesticides, herbicides, and fungicides [1,2], additionally, these contaminants are found in trace concentrations in areas where geological processes and spontaneous combustion occur [3].…”

Section: Introductionmentioning

confidence: 99%

Protection of Resveratrol Against Nephrotoxicity in Rats Produced by 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin

abdallah

2024

Egyptian Journal of Veterinary Sciences

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E CONDUCTED A STUDY to examine the impact of Resveratrol (RES) on the renal tissues of Wistar rats that were exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and developed kidney damage. Applied on albino male rats (102), the age range ( 8-9 ) weeks and the weight range (80 -90) gms, (32) rats were used for acute stage of toxicity, while others (70 ) rats were involved as a chronic toxicity; the experiment design consists of 7 groups ; G1 (control -ve), G2 vehicle ( acetone + corn oil), G3 TCDD ( 4 µg/kg b. w.), G4 TCDD ( 2 µg/kg b. w.), G5 (RES), G6 (TCDD ( 4 µg/kg b. w.)+ RES),G (TCDD( 4 µg/kg b. w.) + RES). We found that malondialdehyde (MDA), urea and creatinine levels in the groups treated with TCDD showed significant increases compared to the other groups, despite a decrease in the levels of reduced glutathione (GSH) and catalase (CAT) in the TCDD groups. Comparing to the other groups, we observed a rise in GSH and CAT levels, as well as a decrease in MDA, urea, and creatinine levels in the RES treated group. The administration of RES improved the oxidative stress markers and histological alterations caused by TCDD.

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Section: Introductionmentioning

confidence: 99%

Protection of Resveratrol Against Nephrotoxicity in Rats Produced by 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin

abdallah

2024

Egyptian Journal of Veterinary Sciences

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“…Leachate formed from chemical reactions in a landfill was one of the major potential contributors of dioxins released to the environment, especially into soil and water bodies (Ferronato & Toretta, 2019). According to Szajner et al (2021), the adverse effects of dioxins on the health of humans and animals were found devastating and irreversible. Dibenzofuran, one of the harmless dioxin congeners, has been chosen as the model in this study.…”

Section: Introductionmentioning

confidence: 99%

Dibenzofuran Degradation by Bacterial Community in Landfill Leachate

Ahmad,

Hadry Nordin,

Abdullah Sani

et al. 2023

JST

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The contamination of the environment has been a global issue, and bioremediation is proposed as an option to clean up the contamination sites with the promising utilization of bacterial community capabilities. The indigenous bacterial community in the landfill leachate is recognized to carry enzymes for the degradation of contaminants such as dioxin congeners, the dibenzofuran. Environmental factors have been known to influence the process to achieve successful biodegradation, and the optimized conditions may speed up the biodegradation process. Thus, this study was conducted to optimize the substrate availability, temperature, and pH factor for the degradation of dibenzofuran from landfill leachate by the native bacterial community in landfill leachate. This study uses the one-factor at-time (OFAT) approach to measure dibenzofuran degradation. The landfill leachate with enrichment of dibenzofuran (15 to 45 mg L-1) was incubated at temperatures (30°C to 42°C) and pH (5 to 9) for 24 hours before being extracted and analyzed. From the first part of the study, 15 mg L-1 of dibenzofuran, 30°C temperature, and pH 7 have shown the highest dibenzofuran degradation. Later, the optimum condition of dibenzofuran removal (74.40%) was achieved when the landfill leachate was spiked with 15 ppm dibenzofuran at 30°C and pH 7 for 24 hours. This study proposes optimized conditions that give a better result for dibenzofuran degradation, which may enhance bioremediation.

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Dioxin-like compounds (DLCs) in the environment and their impact on human health

Cited by 2 publications

References 0 publications

Protection of Resveratrol Against Nephrotoxicity in Rats Produced by 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin

Protection of Resveratrol Against Nephrotoxicity in Rats Produced by 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin

Dibenzofuran Degradation by Bacterial Community in Landfill Leachate

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