Dipstick proteinuria as a surrogate marker of long-term mortality after acute myocardial infarction

Ota, Hisanobu; Takeuchi, Toshiharu; Sato, Nobuyuki; Hasebe, Naoyuki

doi:10.1016/j.jjcc.2013.05.002

Cited by 13 publications

(9 citation statements)

References 20 publications

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“…In some studies, the sensitivity and specificity of the dipstick urinalysis protein ≥ 1+ in detecting the albumin to creatinine ratio ≥ 300 has improved to ≥ 90% [35, 36]. Moreover, proteinuria measured using the dipstick technique itself is a well-validated risk factor for ESRD [2, 3] and mortality [4–6], and is still being used as the main factor or outcome [37–40]. Therefore, this limitation might be marginal.…”

Section: Discussionmentioning

confidence: 99%

Low Rice Intake Is Associated with Proteinuria in Participants of Korea National Health and Nutrition Examination Survey

Lee

Sung

et al. 2017

PLoS ONE

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Little is known about the risk factors of proteinuria in the Asian population. On the basis of the association between rice intake patterns and chronic diseases, we hypothesized that rice intake patterns are associated with proteinuria in the Asian population. Data, including data regarding rice intake frequency and dipstick urinalysis results, from the Korea National Health and Nutrition Examination Survey in 1998, 2001, 2005, and 2007 were analyzed. The study involved 19,824 participants who were older than 20 years of age. Low rice intake was defined as consumption of rice ≤ 1 time/day. Proteinuria was defined as dipstick urinalysis protein ≥ 1 positive. Among the 19,824 participants, the prevalence of low rice intake and proteinuria were 17.3% and 2.9%, respectively. The low rice intake group showed a higher rate of proteinuria than the non-low rice intake group did (3.8% vs. 2.7%, P < 0.001). In multivariate logistic regression analysis, the odds ratio (OR) of low rice intake for proteinuria was 1.54 (95% confidence interval (CI): 1.25–1.89; P < 0.001). Low rice intake was also independently associated with high blood pressure (OR: 1.43, 95% CI: 1.31–1.56; P < 0.001) and diabetes (OR: 1.43, 95% CI: 1.27–1.62; P < 0.001). In conclusion, low rice intake was found to be independently associated with proteinuria in the Asian population, which might have been affected by the associations of low rice intake with high blood pressure and diabetes. Future prospective studies are needed to confirm the results of this study.

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Section: Discussionmentioning

confidence: 99%

Low Rice Intake Is Associated with Proteinuria in Participants of Korea National Health and Nutrition Examination Survey

Lee

Sung

et al. 2017

PLoS ONE

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“…In recent years, there was a proliferation of new scores and methods to predict CIN [13][14][15][16][17][18]; however, their usefulness and extension to clinical practice is limited. The Mehran CIN score was designed in 2004 and based on its simplicity and because it allows early and correct identification of those individuals at high risk for CIN [5], it is currently the most widely used tool for predicting the risk of CIN.…”

Section: Discussionmentioning

confidence: 99%

“…elderly patients, diabetes, renal dysfunction, contrast media volume, heart failure, etc.) [13][14][15][16][17][18][19].…”

Section: Discussionmentioning

confidence: 99%

Mehran contrast nephropathy risk score: Is it still useful 10 years later?

Abellás-Sequeiros

Raposeiras‐Roubín

Abu-Assi

et al. 2016

Journal of Cardiology

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“…Konta et al showed that proteinuria/albuminuria were independently associated with mortality in the Japanese general population [35]. Ota et al and Tonelli et al also investigated all-cause mortality in acute myocardial infarction (AMI) patients [36,37]. Both studies showed that dipstick proteinuria was an independent predictor of all-cause mortality with or without impaired kidney function.…”

Section: Discussionmentioning

confidence: 99%

Mild to moderate proteinuria is a heralding sign for acute kidney injury and mortality for intensive care unit patients

Yeter¹

2019

Turk J Med Sci

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Background/aim: Lack of early predictors of acute kidney injury is currently delaying timely diagnosis. This study was done to evaluate the relationship between mild to moderate proteinuria and incidence of acute kidney injury (AKI) and 28-day mortality in intensive care unit (ICU) patients. Material and methods: This observational, retrospective study was conducted in the internal medicine ICU. A total of 796 patients were screened and 525 patients were used for this analysis. Proteinuria was measured by urine dipstick test. AKI was defined according to the Kidney Disease: Improving Global Outcomes (KDIGO) guidelines. Results: Patients with dipstick urine protein positivity on admission had higher proportion of AKI and 28-day mortality compared to dipstick urine protein negative group [164 (59.6%) vs. 111 (44.4%) and 101 (36.7%) vs. 54 (21.6%), P = 0.01 and P < 0.01, respectively]. Urine dipstick protein positivity was also a significant predictor of 28-day mortality in patients with GFR > 60 mL/min (hazard ratio: 1.988, 95% confidence interval 1.380-2.862). Conclusion: Proteinuria before ICU admission is a risk factor for development of AKI within seven days of ICU stay and also is a risk factor for 28-day mortality, even in patients with GFR > 60 mL/min.

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Dipstick proteinuria as a surrogate marker of long-term mortality after acute myocardial infarction

Abstract: Dipstick proteinuria and lower eGFR in the early phase of AMI follow-up were related to increased plasma BNP level during the sub-acute phase and long-term adverse outcome. Dipstick proteinuria may be a prognostic marker for long-term all-cause mortality.

Cited by 13 publications

References 20 publications

Low Rice Intake Is Associated with Proteinuria in Participants of Korea National Health and Nutrition Examination Survey

Low Rice Intake Is Associated with Proteinuria in Participants of Korea National Health and Nutrition Examination Survey

Mehran contrast nephropathy risk score: Is it still useful 10 years later?

Mild to moderate proteinuria is a heralding sign for acute kidney injury and mortality for intensive care unit patients

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