Direct determination of melamine in dairy products by gas chromatography/mass spectrometry with coupled column separation

Xu, Xia; Ren, Yiping; Zhu, Yuxiang; Cai, Zengxuan; Han, Jiaguang; Huang, Baifen; Zhu, Yan

doi:10.1016/j.aca.2009.04.026

Cited by 178 publications

(73 citation statements)

References 8 publications

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“…Thus, peoples pay attention to the detection of melamine, and it is necessary to develop simple and fast, sensitive and selective, and inexpensive methods to detect melamine. At present, several methods, including gas chromatographymass spectrophotometry, high-performance liquid chromatography (HPLC), HPLC-mass spectrometry, and Raman spectral method [5][6][7][8][9][10][11], have been reported for detecting melamine, with good results. Recently, some new techniques such as the resonance scattering (RS) analytical technique and new reagents including nanoparticle and aptamer are utilized in analytical chemistry.…”

Section: Introductionmentioning

confidence: 99%

A Simple and Sensitive Resonance Scattering Spectral Assay for Detection of Melamine Using Aptamer-Modified Nanosilver Probe

Liang

Zhou

2011

Plasmonics

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Nanosilver of 10-nm size was prepared by the NaBH 4 -sodium citrate procedure, and it was modified by a single-strand DNA (ssDNA) aptamer to fabricate an AgssDNA probe for melamine. The probe was stabile at pH 7.0 Na 2 HPO 4 -NaH 2 PO 4 buffer solutions and in the presence of 25.0 mmol/L NaCl. Upon the addition of melamine, it interacted with the probe to aggregate big clusters, which led to the resonance scattering (RS) intensity at 470 nm increasing greatly. Under the selected conditions, the increased RS intensity (ΔI 470 nm ) is linear to melamine concentration in the range of 6.31-378.4 μg/L, with a regression equation of $I 470nm ¼ 1:124c þ 10:8 and a detection limit of 3.1 μg/L. The aptamer-modified nanosilver RS assay has been applied for the determination of melamine in milk, with satisfactory results.

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Section: Introductionmentioning

confidence: 99%

A Simple and Sensitive Resonance Scattering Spectral Assay for Detection of Melamine Using Aptamer-Modified Nanosilver Probe

Liang

Zhou

2011

Plasmonics

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“…Numerous methods have been reported for the determination of melamine, such as capillary electrophoresis [6], high performance liquid chromatography [7], gas chromatographymass spectrometry [8], fluorescence [9], colorimetric method [10,11] surface enhanced Raman scattering [12] or electrochemical technique [13]. Relative to other methods, electrochemical technique has great advantages, such as fast response, time saving, simple operation and high sensitivity.…”

Section: Introductionmentioning

confidence: 99%

Determination of melamine in food contact materials using an electrode modified with gold nanoparticles and reduced graphene oxide

Chen

Cheng

et al. 2015

Microchim Acta

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We describe an electrochemical sensor for melamine based on a glassy carbon electrode (GCE) modified with reduced graphene oxide that was decorated with gold nanoparticles (AuNP/rGO). The AuNPs/rGO nanocomposite was synthesized by co-reduction of Au(III) and graphene oxide and characterized by transmission electron microscopy, Raman spectroscopy, X-ray diffraction and X-ray photoelectron spectroscopy. The response of the modified GCE to melamine was investigated by using hexacyanoferrate as an electrochemical reporter. It is found that the electrochemical response to hexacyanoferrate is increasingly suppressed by increasing concentration of melamine. This is attributed to competitive adsorption of melamine at the AuNP/rGO composite through the interaction between the amino groups of melamine and the AuNPs. The presence of rGO, in turn, provides a platform for a more uniform distribution of the AuNPs and enhances the electron transfer rate of the redox reaction. The findings were used to develop a sensitive method for the determination of melamine. Under optimized conditions, the redox peak current of hexacyanoferrate at a working voltage of 171 mV (vs. SCE) is linearly related to the concentration of melamine in 5.0 to 50 nM range. The method was successfully applied to the determination of melamine in food contact materials.

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“…Up to September 22, 2008, a total of 52,857 cases of nephrolithiasis have been reported; in some cases, renal failure, 12,900 hospitalization and 4-6 deaths from various regions in China have been reported, all of which were traced back to consumption of melamine-contaminated powdered milk products. Test results conducted in China on samples of powdered infant formula showed that samples contained a wide range of concentrations (0.1-[2,500 ppm) melamine powder (Xu et al 2009;Afoakwa 2008). Soon after these tests, various dairy and nondairy products originating from China were found contaminated with melamine (Gossner et al 2009).…”

Section: Introductionmentioning

confidence: 99%

Assessment of residue melamine in dairy products exhibited in Zanjan market, Iran by high-performance liquid chromatography method

Poorjafari

Zamani

Mohseni³

et al. 2014

Int. J. Environ. Sci. Technol.

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An increasing number of infants are being made sick by dairy products contaminated with melamine. As a result, many countries have adopted additional requirements for milk-based food products. The scope of the present study was to assess amounts of melamine in some dairy products from Zanjan market, Iran. Amounts of melamine in samples of milk, yoghurt, infant formula, coffee mate and cheese were determined in five different brands by the high-performance liquid chromatography with ultraviolet detector system. In total, 225 samples were determined (five products 9 five brands 9 three samples 9 three repeated measurements). Amounts of melamine in samples (in lg/g) were determined in the range of 0.20-0.26 for milk, 0.57-0.99 for yoghurt, 0.35-3.40 for infant formula, 0.09-1.23 for coffee mate and 0.30-2.50 for cheese, and the mean values of melamine in products were evaluated as 0.24, 0.76, 1.38, 0.56 and 1.16, respectively. The minimum and maximum values for amounts of melamine were recorded in milk and infant formula, respectively. Comparison of test results with the standards set by the European Union and the US Food and Drug Administration for maximum residue-level values for dairy products contaminated with melamine showed that levels determined by tests had higher health risks than the regulations allowed. Iran has not yet adopted regulations to control levels of melamine in food products. The results show that maximum residue-level values need to be determined for melamine in Iranian dairy products, and foods should be monitored daily for levels of melamine contamination.

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Direct determination of melamine in dairy products by gas chromatography/mass spectrometry with coupled column separation

Cited by 178 publications

References 8 publications

A Simple and Sensitive Resonance Scattering Spectral Assay for Detection of Melamine Using Aptamer-Modified Nanosilver Probe

A Simple and Sensitive Resonance Scattering Spectral Assay for Detection of Melamine Using Aptamer-Modified Nanosilver Probe

Determination of melamine in food contact materials using an electrode modified with gold nanoparticles and reduced graphene oxide

Assessment of residue melamine in dairy products exhibited in Zanjan market, Iran by high-performance liquid chromatography method

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